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75950

Sigma-Aldrich

2-Oxovaleric acid

≥98.0% (T)

Synonym(s):

α-Ketovaleric acid, 2-Oxopentanoic acid

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About This Item

Linear Formula:
CH3CH2CH2COCOOH
CAS Number:
1821-02-9
Molecular Weight:
116.12
Beilstein:
635884
EC Number:
217-340-2
MDL number:
MFCD00066435
UNSPSC Code:
12352100
PubChem Substance ID:
57652597
NACRES:
NA.22

Quality Level

100

Assay

≥98.0% (T)

form

liquid

bp

88-90 °C/12 mmHg (lit.)

mp

7-9 °C (lit.)

density

1.110 g/mL at 20 °C (lit.)

storage temp.

2-8°C

SMILES string

CCCC(=O)C(O)=O

InChI

1S/C5H8O3/c1-2-3-4(6)5(7)8/h2-3H2,1H3,(H,7,8)

InChI key

KDVFRMMRZOCFLS-UHFFFAOYSA-N

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

201.2 °F - closed cup

Flash Point(C)

94 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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C Coronel et al.
Molecular and biochemical parasitology, 4(1-2), 29-38 (1981-11-01)
Whole cell extracts of culture epimastigotes of Trypanosoma cruzi (Tulahuén strain) have alpha-hydroxyacid dehydrogenase activity which catalyzes the NAD-linked reaction alpha-ketoacid in equilibrium with alpha-hydroxyacid, with a variety of substrates. Two molecular forms of the enzyme have been separated by
R Sakowicz et al.
Biochemistry, 32(47), 12730-12735 (1993-11-30)
Threonine 246 is an active site residue that is conserved in all known L-lactate dehydrogenase (LDH; EC 1.1.1.27) sequences. In order to investigate the role of Thr246 in Bacillus stearothermophilus LDH, this residue was altered by site-directed mutagenesis to valine
Tara Kearney et al.
Metabolism: clinical and experimental, 52(1), 50-59 (2003-01-14)
In this study, we concurrently examined the effects of 8 and 40 weeks of growth hormone replacement (GHR) on lipids, lipoprotein composition, low-density lipoprotein (LDL) size, very-low-density lipoprotein (VLDL) apolipoprotein (apo)B kinetics and LDL apoB kinetics. Eight weeks of GHR
Carmen Martínez-Cuesta et al.
FEMS microbiology letters, 217(1), 109-113 (2002-11-26)
The effect of the bacteriocin lacticin 3147 on the branched-chain amino acid transamination by Lactococcus lactis IFPL359 was investigated. The bacteriocin provokes membrane permeabilisation of the cells, rendering them non-viable but metabolically active. Free diffusion of amino acids into the
R Bränström et al.
The Journal of biological chemistry, 273(23), 14113-14118 (1998-06-11)
The ATP-regulated potassium (KATP) channel plays an essential role in the control of insulin release from the pancreatic beta-cell. In the present study we have used the patch-clamp technique to study the direct effects of alpha-ketoisocaproate on the KATP channel
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