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742031

Sigma-Aldrich

Gold nanoparticles

100 nm diameter, OD 1, stabilized suspension in citrate buffer

Synonym(s):

Au NP, Gold Colloid

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About This Item

MDL number:
MFCD00003436
UNSPSC Code:
12352302
PubChem Substance ID:
329765552
NACRES:
NA.23
Pricing and availability is not currently available.

form

nanoparticles
suspension

contains

Proprietary Surfactant as stabilizer

concentration

~3.8E+9 particles/mL

OD

1

diameter

100 nm

λmax

565-574 nm

PDI

<0.2

storage temp.

2-8°C

SMILES string

[Au]

InChI

1S/Au

InChI key

PCHJSUWPFVWCPO-UHFFFAOYSA-N

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General description

Gold nanoparticles (AuNPs) are quasi-dynamic materials that have high stability,high surface to volume ratio, high conductivity, and low toxicity. AuNPs are commercially used for various biomedical, electrochemical and energy based applications.[1][2][3][4][5]

Application

Ideal for adsorption of thiolated ligands such as oligonucleotides and polyethylene glycols. Also, due to the increased stability, these gold nanoparticles are ideal for use in physical and optical applications. Note: This product is not ideal for protein adsorption. For gold nanoparticles suitable for adsorption of proteins and other ligands for conjugate development, please see our gold nanoparticles stabilized in PBS.

This material is highly monodisperse (<12% variability in size and shape), and provides significantly improved surface reactivity. Applications include Surface Enhanced Raman Lables, Sensing/Detection, Biological Targeting, Plasmonics and Electronics.

Legal Information

Product of CytoDiagnostics, Inc.

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW6833
MKCT8194
MKCS3830
MKCS5877
MKCR7075

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Gold Nanoparticles For Physics, Chemistry And Biology (Second Edition) (2012)
Gold nanoparticles for applications in energy and environment: synthesis and characterization
Chen Y
Rare Metals, 30(1), 116-120 (2011)
Spectroscopic Study of the Interaction of Carboxyl-Modified Gold Nanoparticles with Liposomes of Different Chain Lengths and Controlled Drug Release by Layer-by-Layer Technology
Kanwa N, et al.
The Journal of Physical Chemistry B, 121(50), 11333-11343 (2017)
Graphene-gold nanoparticles hybrid?synthesis, functionalization, and application in a electrochemical and surface-enhanced raman scattering biosensor
Khalil I, et al.
Materials, 9(6), 406-406 (2016)
Gold nanoparticles: preparation, properties, and applications in bionanotechnology
Yeh Y, et al.
Nanoscale, 4(6), 1871-1880 (2012)

Articles

Sensitivity Lateral Flow Diagnostic Assays

Steven J. Oldenburg, Ph.D. provides an overview of lateral flow diagnostic assays and discusses the use of ultra-bright reporter particles based on the unique optical properties of gold nanoshells that significantly increase the sensitivity of lateral flow immunoassays.

Sensitivity Lateral Flow Diagnostic Assays

Steven J. Oldenburg, Ph.D. provides an overview of lateral flow diagnostic assays and discusses the use of ultra-bright reporter particles based on the unique optical properties of gold nanoshells that significantly increase the sensitivity of lateral flow immunoassays.

Surface-enhanced Solar Energy Conversion Systems

Sustainable energy sources with high production efficiency are crucial for meeting increasing energy demand.

Sensitivity Lateral Flow Diagnostic Assays

Steven J. Oldenburg, Ph.D. provides an overview of lateral flow diagnostic assays and discusses the use of ultra-bright reporter particles based on the unique optical properties of gold nanoshells that significantly increase the sensitivity of lateral flow immunoassays.

See All

Questions

1–10 of 16 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. What are the contents in citrate buffer and the concentration of each of them? Moreover, what is the PH of the citrate buffer? Or do you have any citrate buffer product is same as this stabilized suspension?

    1 answer

    1. 742031 is gold nanoparticles in citrate buffer that comes from the external supplier: CytoDiagnostics, Inc Unfortunately, the contents and concentration of components in citrate buffer is proprietary. Hence, there is no citrate buffer product guaranteed to be the same as the stabilized suspension. The vendor's SDS shows the pH of this product is 6-8: https://portal.cytodocs.com/documents/SDS/Stabilized-Gold-Nanoparticles-SDS.pdf

      Helpful?

  4. What is the viscosity and the refractive index of its citrate buffer?

    1 answer

    1. Unfortunately, the viscosity and refractive index are not test specifications for this product.

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  5. How to make sure the concentration of the gold nanoparticles (Particles/ml)

    1 answer

    1. The concentration is listed as a test specification on the certificate of analysis. The concentration will be a confirmed result of 3.45E+9-4.22E+9 particles/m

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  6. How does the storage temperature relate to shipping conditions?

    1 answer

    1. The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.

      Helpful?

  7. My gold nanoparticles settle out of solution upon storage. Is this normal?

    1 answer

    1. Settling of gold nanoparticles on the bottom of the storage flask is completely normal and is especially common for larger sized particles, which settles at greater speed. Settling does not affect the performance of the particles. Prior to use, simply swirl the solution to properly disperse your gold nanoparticles and obtain a homogenous solution.

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  8. How do you attach gold nanoparticles to glass?

    1 answer

    1. To view the procedure on how to attach gold nanoparticles to glass please view information in the reference - Journal of Atomic, Molecular, and Optical PhysicsVolume 2012 (2012). Article ID 683830, 6 pagesdoi:10.1155/2012/683830

      Helpful?

  9. Can the Gold nanoparticles be frozen?

    1 answer

    1. No, the Gold nanoparticles should not be frozen.  If frozen, the gold nanoparticles will irreversibly aggregate, turning the solution clear.

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  10. How do you attach gold nanoparticles to oligos?

    1 answer

    1. To attach gold nanoparticles to oligos please view the information in the attached reference - Bioconjug Chem. 2011 Apr 20;22(4):794-807. Epub 2011 Mar 28.

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1–10 of 16 Questions  

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