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Supelco

SUPELCOSIL™ LC-18-DB (5 µm) HPLC Columns

L × I.D. 15 cm × 4.6 mm, HPLC Column

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About This Item

UNSPSC Code:
41115700
eCl@ss:
32110501

product name

SUPELCOSIL™ LC-18-DB HPLC Column, 5 μm particle size, L × I.D. 15 cm × 4.6 mm

Agency

suitable for USP L1

feature

endcapped

manufacturer/tradename

SUPELCOSIL™

extent of labeling

11.0% Carbon loading

parameter

0-70 °C temperature
400 bar pressure (5801 psi)

technique(s)

HPLC: suitable

L × I.D.

15 cm × 4.6 mm

surface area

170 m2/g

surface coverage

surface coverage 3.1 μmol/m2

matrix

silica gel, spherical particle platform

matrix active group

C18 (octadecyl) phase

particle size

5 μm

pore size

120 Å

application(s)

food and beverages

separation technique

reversed phase

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General description

SUPELCOSIL LC-DB phases are specially deactivated for basic compounds. These columns provide shorter retention, better peak shape, and higher efficiency for organic bases than can be obtained on other Type A silica reversed-phase columns.

Application

SUPELCOSIL™ LC-18-DB HPLC Column has been used for the separation of:
  • Analytes of pharmaceutical relevance during their analysis using LC in conjunction with principal component analysis (PCA).
  • Loratadine in human plasma during its analysis by using HPLC combined with ultraviolet (UV) detection.

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Legal Information

SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
292349-06
292349-05
292349-04
292349-03
292349-02

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Determination of loratadine in human plasma by high-performance liquid chromatographic method with ultraviolet detection.
Kunicki PK.
Journal of Chromatography. B, Biomedical Sciences and Applications, 755(1-2), 331-335 (2001)
Chromatographic classification and comparison of commercially available reversed-phase liquid chromatographic columns using principal component analysis
Euerby MR and Petersson P
Journal of Chromatography A, 994(1-2), 13-36 (2003)
Jaganathan Subramani et al.
Aging, 12(19), 19809-19827 (2020-10-14)
Aging is an independent risk factor for cardiovascular diseases, such as myocardial infarction due to ischemia-reperfusion injury (I/R) of the heart. Cytosolic thioredoxin (Trx) is a multifunctional redox protein which has antioxidant and protein disulfide reducing properties. We hypothesized that
S L Bramer et al.
Journal of pharmaceutical and biomedical analysis, 26(4), 637-650 (2001-08-23)
An LC/MS/MS method for the simultaneous determination of cilostazol, a quinolinone derivative, and three active metabolites, OPC-13015, OPC-13213, and OPC-13217, in human plasma was developed and validated. Cilostazol, its metabolites, and the internal standard, OPC-3930 were extracted from human plasma
O Majid et al.
Therapeutic drug monitoring, 23(2), 163-168 (2001-04-11)
Recipients of organ transplants remain particularly dependent on prednisolone as part of their maintenance immunosuppression. Despite this, the pharmacokinetics of prednisolone have never been fully characterized in these patients, and consequently dosing remains empirical. Accurate monitoring of prednisolone, its primary
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