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SML3602

Sigma-Aldrich

Pipobroman

≥98% (HPLC)

Synonym(s):

1,​1′-​(1,​4-​Piperazinediyl)​bis[3-​bromo-1-​propanone, 1,​4-​bis(3-​Bromo-​1-​oxopropyl)​-piperazine, N,N-Bis-(3-bromopropionyl)-piperazine, NSC-​25154

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About This Item

Empirical Formula (Hill Notation):
C10H16Br2N2O2
CAS Number:
54-91-1
Molecular Weight:
356.05
MDL number:
MFCD00866372
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

Biochem/physiol Actions

Pipobroman is an alkylating agent that is used as anti-cancer drug. It also has clinical activity in polycythemia vera and thrombocythemia.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Jean-Jacques Kiladjian et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 29(29), 3907-3913 (2011-09-14)
The overall impact of hydroxyurea (HU) or pipobroman treatments on the long-term outcome of patients with polycythemia vera (PV) has not been assessed in randomized studies. We report final analyses from the French Polycythemia Study Group (FPSG) study, which randomly
Giovanni Fazio et al.
Journal of thrombosis and thrombolysis, 35(2), 282-285 (2012-07-31)
Polycythemia vera (PV) is a chronic myeloproliferative disorder characterized by an abnormal increase in red blood cells. The involvement of the heart during the course of the illness represents a common cause of morbidity and it is linked to an

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