G5889

L-Glutamic acid monosodium salt hydrate

BioReagent, suitable for cell culture, suitable for insect cell culture, ≥99%

• Synonym(s): (S)-2-Aminopentanedioic acid, L-Glutamic acid monosodium salt, Glu, MSG, Monosodium glutamate
• Empirical Formula (Hill Notation): C₅H₈NNaO₄ · xH₂O
• CAS Number: 142-47-2
• Molecular Weight: 169.11 (anhydrous basis)
• EC Number: 205-538-1
• MDL number: MFCD00013074
• UNSPSC Code: 12352209
• PubChem Substance ID: 24895237
• NACRES: NA.75

Properties

• product line: BioReagent
• Assay: ≥99%
• form: powder
• technique(s): cell culture | insect: suitable; cell culture | mammalian: suitable
• color: white to off-white
• mp: 163 °C
• InChI: 1S/C5H9NO4.Na.H2O.H/c6-3(5(9)10)1-2-4(7)8;;;/h3H,1-2,6H2,(H,7,8)(H,9,10);;1H2;
• InChI key: JYDGDQPVBSBYRT-UHFFFAOYSA-N

Description

General description

L-Glutamic acid/monosodium glutamate (MSG) is the sodium salt of glutamic acid. It is a commonly used food additive.

Application

L-Glutamic acid monosodium salt hydrate has been used:

• to prepare glutamate stock solution in HEPES-buffered saline (HBS) for glutamate perfusions
• as a component in YNG (yeast nitrogen base glutamate) medium
• used to treat HT22 hippocampal cells to study its effects on cell viability and to examine the expression of molecules related to apoptotic cell death
• as a component of fresh media to culture neurons and to assess glutamate uptake

Biochem/physiol Actions

Monosodium glutamate (MSG) is a food additive and an environmental agent, that can affect inflammation.

Agonist at kainate, NMDA, and quisqualate receptors; an excitatory amino acid neurotransmitter.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves