Skip to Content
Merck
All Photos(1)

Documents

16005

Sigma-Aldrich

Brij® L23

main component: tricosaethylene glycol dodecyl ether

Synonym(s):

Brij 35, C12E23, Polyoxyethylene (23) lauryl ether

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

CAS Number:
9002-92-0
MDL number:
MFCD00080891
UNSPSC Code:
12161900
PubChem Substance ID:
57647536
NACRES:
NA.21

description

non-ionic

form

pellets

CMC

91 μM

mp

39-43 °C

HLB value

16.9

solubility

H2O: 40 mg/mL at 20 °C, clear to slightly hazy, colorless

cation traces

Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤500 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤500 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C58H118O24/c1-2-3-4-5-6-7-8-9-10-11-13-60-15-17-62-19-21-64-23-25-66-27-29-68-31-33-70-35-37-72-39-41-74-43-45-76-47-49-78-51-53-80-55-57-82-58-56-81-54-52-79-50-48-77-46-44-75-42-40-73-38-36-71-34-32-69-30-28-67-26-24-65-22-20-63-18-16-61-14-12-59/h59H,2-58H2,1H3

InChI key

IEQAICDLOKRSRL-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Brij®L23 is a detergent used for measuring the concentration of carbon black in lung tissues. It has also been used for selective and rapid solubilization of microbial membrane aldehyde dehydrogenase. Additionally, the product has also been used for assessing whether acrolein could lead to pro-enzyme activation by using gelatin zymography.

Biochem/physiol Actions

Brij® L23 also referred to as Brij 35 or Polyoxyethylene (23) lauryl ether is a non-ionic detergent that lowers the non-specific protein adsorption and reduces electroosmotic pumping drastically. This allows the pH to be varied without adversely affecting the flow rate. It also used as a nonionic surfactant that decreases the absorbance of the blank, inhibits turbidity as well as provides linearity.

Other Notes

Non-ionic polyoxyethylene ether. Used for selective and rapid solubilization of microbial membrane aldehyde dehydrogenase.

Legal Information

Brij is a registered trademark of Croda International PLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

>300.2 °F - closed cup

Flash Point(C)

> 149 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

J K Towns et al.
Analytical chemistry, 63(11), 1126-1132 (1991-06-01)
Capillary zone electrophoretic separations of proteins have been achieved by using nonionic surfactant coated capillaries. Capillaries were prepared by derivatization of the silica surface with octadecylsilane followed by the deposition of a layer of nonionic surfactant from an aqueous solution
Cheol-Hong Lim et al.
Environmental health and toxicology, 28, e2013014-e2013014 (2013-12-05)
This study was conducted to determine whether nano-sized carbon black exposure results in greater damage in high fat diet-induced overweight rats than normal weight ones and to identify the possible causes of any differences. Two groups of Sprague-Dawley rats allocated
B T Dumas et al.
Clinica chimica acta; international journal of clinical chemistry, 258(1), 21-30 (1997-02-03)
A rapid and reliable method for measuring serum albumin employing bromcresol green is described. The addition of albumin to a solution of bromcresol green in a 0.075 M succinate buffer pH 4.20 results in an increase in absorbance at 628
Johanna Zemva et al.
Redox biology, 13, 674-686 (2017-08-22)
Energy production is inevitably linked to the generation of toxic metabolites, such as reactive oxygen and carbonyl species, known as major contributors to ageing and degenerative diseases. It remains unclear how cells can adapt to elevated energy flux accompanied by
Xiaohong Ye et al.
Nature communications, 10(1), 1463-1463 (2019-04-02)
Retinoid X receptor-alpha (RXRα) is a potent regulator of inflammatory responses; however, its therapeutic potential for inflammatory cancer remains to be explored. We previously discovered that RXRα is abnormally cleaved in tumor cells and tissues, producing a truncated RXRα (tRXRα).
View All Related Papers

Articles

Electronics and Self-Assembly with Single Molecules

Single molecule electronics is the endeavour of constructing electronic circuitry with single molecules as the fundamental building block.

Electronics and Self-Assembly with Single Molecules

Single molecule electronics is the endeavour of constructing electronic circuitry with single molecules as the fundamental building block.

Electronics and Self-Assembly with Single Molecules

Single molecule electronics is the endeavour of constructing electronic circuitry with single molecules as the fundamental building block.

Electronics and Self-Assembly with Single Molecules

Single molecule electronics is the endeavour of constructing electronic circuitry with single molecules as the fundamental building block.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service