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AB9726

Sigma-Aldrich

Anti-Serotonin Transporter Antibody

serum, Chemicon®

Synonym(s):

Serotonin transporter antibody

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, rat

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

Specificity

Serotonin Transporter. By Western blot the antibody recognizes a strong band at ~64 kDa in rat brain extract. The antibody is suitable for detection of the serotonin transporter in the CNS, PNS and peripheral organs where the transporter is present.

Immunogen

Fusion protein from the N-terminal of rat Serotonin Transporter.

Application

Anti-Serotonin Transporter Antibody is an antibody against Serotonin Transporter for use in IH, IP & WB.
Immunohistochemistry on 4% paraformaldehyde fixed tissues.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters

Physical form

Liquid

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yong Li et al.
Frontiers in cellular neuroscience, 12, 241-241 (2018-08-24)
Parkinson's disease (PD) is characterized not only by typical motor symptoms, but also by nonmotor symptoms in the early stages. In addition to the loss of dopaminergic (DAergic) neurons, progressive degenerations of noradrenergic (NA) and serotonergic (5-HT) neurons were also
Shuming An et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(28), 9511-9516 (2012-07-13)
Long-term potentiation (LTP) is important for the activity-dependent formation of early cortical circuits. In the neonatal rodent barrel cortex, LTP has been studied only in vitro. We combined voltage-sensitive dye imaging with extracellular multielectrode recordings to study whisker stimulation-induced LTP
Roberto Chiocchetti et al.
Frontiers in veterinary science, 8, 802479-802479 (2022-01-25)
Serotonin is crucial in gastrointestinal functions, including motility, sensitivity, secretion, and the inflammatory response. The serotonin transporter (SERT), responsible for serotonin reuptake and signaling termination, plays a prominent role in gastrointestinal physiology, representing a promising therapeutic target in digestive disorders.
Lucina E Lizarraga et al.
Toxicological sciences : an official journal of the Society of Toxicology, 143(1), 209-219 (2014-11-06)
3,4-(±)-Methylenedioxymethamphetamine (MDMA, Ecstasy) is a ring-substituted amphetamine derivative with potent psychostimulant properties. The neuropharmacological effects of MDMA are biphasic in nature, initially causing synaptic monoamine release, primarily of serotonin (5-HT). Conversely, the long-term effects of MDMA manifest as prolonged depletions
Michael J Seminerio et al.
Pharmacology, biochemistry, and behavior, 98(1), 12-20 (2010-12-07)
Methamphetamine interacts with sigma (σ) receptors and AC927, a selective σ receptor ligand, protects against methamphetamine-induced dopaminergic neurotoxicity. In the present study, the effects of AC927 on methamphetamine-induced hyperthermia and striatal serotonergic neurotoxicity were evaluated. Male, Swiss Webster mice were

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