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05-724MG

Sigma-Aldrich

Anti-Myc Tag Antibody, clone 4A6

clone 4A6, Upstate®, from mouse

Synonym(s):

Anti-Myc Antibody, Clone 4A6 Anti-Myc Tag, Myc Tag Detection Antibody

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.43

biological source

mouse

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

4A6, monoclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

immunocytochemistry: suitable
immunofluorescence: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... MYC(4609)

General description

Recognizes and is specific for recombinant proteins containing the Myc epitope tag (EQKLISEEDL) in a variety of sequence contexts. Also recognizes human Myc.

Specificity

Recognizes and is specific for recombinant proteins containing the Myc epitope tag (EQKLISEEDL) in a variety of sequence contexts; also recognizes human Myc.

Immunogen

peptide corresponding to amino acids 410-420 (MEQKLISEEDL) of human Myc

Application

Detect Myc Tag using this Anti-Myc Tag Antibody, clone 4A6 validated for use in ChIP, IF, IP, WB & IC.
Research Category
Epitope Tags & General Use
Research Sub Category
Epitope Tags

Quality

routinely evaluated by immunoblot on Myc-tagged recombinant protein in sequence contexts

Target description

dependent upon the molecular weight of the tagged protein

Physical form

Format: Purified
PBS
Protein G Purified

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yi-Chao Lee et al.
Journal of biomedical science, 25(1), 76-76 (2018-11-09)
The brain predominantly expressed RING finger protein, Znf179, is known to be important for embryonic neuronal differentiation during brain development. Downregulation of Znf179 has been observed in motor neurons of adult mouse models for amyotrophic lateral sclerosis (ALS), yet the
Yu-Jung Chang et al.
Cancers, 12(10) (2020-10-07)
Increased ROS proto-oncogene 1 (ROS1) expression has been implicated in the invasiveness of human oral squamous cell carcinoma (OSCC). The cellular distribution of ROS1 has long-been assumed at the plasma membrane. However, a previous work reported a differential cellular distribution
Sahasransu Mahapatra et al.
Nucleic acids research, 39(10), 4023-4034 (2011-01-27)
FACT complex is involved in elongation and ensures fidelity in the initiation step of transcription by RNA polymerase (pol) II. Histone variant H2A.Z is found in nucleosomes at the 5'-end of many genes. We report here H2A.Z-chaperone activity of the
Roeland Lameris et al.
Immunology, 149(1), 111-121 (2016-06-18)
Ligation of the CD1d antigen-presenting molecule by monoclonal antibodies (mAbs) can trigger important biological functions. For therapeutic purposes camelid-derived variable domain of heavy-chain-only antibodies (VHH) have multiple advantages over mAbs because they are small, stable and have low immunogenicity. Here
Yvonne Hackmann et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(47), E4482-E4491 (2013-11-07)
Mutations in either syntaxin 11 (Stx11) or Munc18-2 abolish cytotoxic T lymphocytes (CTL) and natural killer cell (NK) cytotoxicity, and give rise to familial hemophagocytic lymphohistiocytosis (FHL4 or FHL5, respectively). Although Munc18-2 is known to interact with Stx11, little is

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