SML3810
p-Nitrobenzyl mesylate
≥98% (HPLC)
Synonym(s):
4-Nitro-benzenemethanol Methanesulfonate, 4-Nitrobenzyl Mesylate, PNBM
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About This Item
Empirical Formula (Hill Notation):
C8H9NO5S
CAS Number:
Molecular Weight:
231.23
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.21
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Quality Level
Assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Biochem/physiol Actions
p-Nitrobenzyl mesylate (PNBM) is a thiol-specific alkylating reagent for direct kinase substrate identification. p-Nitrobenzyl mesylate (PNBM) alkylates thiophosphorylated proteins to form thiophosphate ester epitopes that can be detected by thiophosphate-ester-specific antibody by immunoblotting, immunoprecipitation or immunoaffinity purification.
Caution
Hygroscopic
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
PKC?/? inhibition activates an ULK2-mediated interferon response to repress tumorigenesis
Molecular Cell, 81(21), 4509-4526 (2021)
A semisynthetic epitope for kinase substrates
Nature Methods, 4(6), 511-516 (2007)
Identification of AMPK Phosphorylation Sites Reveals a Network of Proteins Involved in Cell Invasion and Facilitates Large-Scale Substrate Prediction
Cell Metabolism, 22(5), 907-921 (2015)
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