SAB4200464

Anti-WDR37 antibody, Mouse monoclonal

clone WDR37-9, purified from hybridoma cell culture

• Synonym(s): Monoclonal Anti-RP11-529L18.2, Monoclonal Anti-WD repeat domain 37, Monoclonal Anti-WDR37 antibody produced in mouse
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: mouse
• conjugate: unconjugated
• antibody form: purified from hybridoma cell culture
• antibody product type: primary antibodies
• clone: WDR37-9, monoclonal
• form: buffered aqueous solution
• mol wt: antigen ~55 kDa
• species reactivity: human, mouse
• concentration: ~1.0 mg/mL
• technique(s): indirect immunofluorescence: 2.5-5.0 μg/mL using A431 cells.; western blot: 3.0-6.0 μg/mL using U87 total cell extracts.
• isotype: IgG1
• UniProt accession no.: Q9Y2I8
• shipped in: dry ice
• storage temp.: −20°C
• Gene Information: human ... WDR37(22884) ; mouse ... Wdr37(207615)

Description

General description

WDR37 (WD repeat- containing protein 37), is a 494 amino acid protein that contains seven WD-repeats. WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. The gene encoding WDR37 maps to human chromosome 10q15.3. WDR37 gene is located in loci responsible for renal function and chronic kidney disease (CKD).

Immunogen

synthetic peptide corresponding to a sequence at the N-terminus of human WDR37, conjugated to KLH. The isotype is determined by ELISA using Mouse Monoclonal Antibody Isotyping Reagents (Sigma ISO-2).

Application

Monoclonal Anti-WDR37 antibody produced in mouse has been used in:

• immunofluorescence
• immunoblotting
• immunohistochemistry
• immunocytochemistry

Biochem/physiol Actions

Proteins containing WD-repeats participate in a wide range of cellular functions, such as chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable