SAB3501273

Anti-Sin Nombre Virus Glycoprotein 2 antibody produced in rabbit

affinity isolated antibody

• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: liquid
• species reactivity: virus (Sin Nombre virus)
• concentration: 1 mg/mL
• technique(s): ELISA: suitable
• isotype: IgG
• NCBI accession no.: NP_941974
• UniProt accession no.: Q89905
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: Sin Nombre virus ... SNVsMgp1(2654026)

Description

General description

Sin Nombre virus (SNV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS). Hantavirus glycoprotein precursor (GPC) is posttranslationally cleaved into two glycoproteins G1 (Gn) and G2 (Gc). While the G1 glycoprotein is is thought to be degraded by the host autophagy machinery, and this autophagic clearance is required for efficient virus repliaction , no such degradation was observed for the G2 glycoprotein.

Immunogen

Sin Nombre virus glycoprotein 2 antibody was raised against a 16 amino acid peptide near the center of the Sin Nombre virus glycoprotein.The immunogen is located within amino acids 670 - 720 of Sin Nombre Virus Glycoprotein 2.

Application

Sin Nombre virus glycoprotein 2 antibody can detect 10ng Sin Nombre virus glycoprotein 2 peptide in ELISA at 1 μg/ml.

Physical form

Supplied in PBS containing 0.02% sodium azide.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable