a 17 amino acid peptide from near the carboxy-terminus of human Nicastrin.
Linkage
The action of this antibody can be blocked using blocking peptide SBP3983.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide
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Frontiers in neuroscience, 14, 591138-591138 (2021-02-02)
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by changes in cognitive and behavioral functions. With the exception or rare mutations in PSEN and APP genes causing early-onset autosomal dominant AD (EOADAD), little is known about the genetic factors
Our studies reveal changes in the expression of the main participants in the processing of amyloid precursor protein (APP) in neurons and astrocytes after photothrombotic stroke (PTS). Here we show the increase in the level of N- and C-terminal fragments
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