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P7780

Sigma-Aldrich

Propionylpromazine hydrochloride

Synonym(s):

Propiopromazine hydrochloride

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500 MG
$413.00

$413.00


Estimated to ship on16 April 2025


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500 MG
$413.00

About This Item

Empirical Formula (Hill Notation):
C20H24N2OS · HCl
CAS Number:
Molecular Weight:
376.94
Beilstein:
38502
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

$413.00


Estimated to ship on16 April 2025


Request a Bulk Order

form

powder

Quality Level

storage temp.

2-8°C

SMILES string

Cl.CCC(=O)c1ccc2Sc3ccccc3N(CCCN(C)C)c2c1

InChI

1S/C20H24N2OS.ClH/c1-4-18(23)15-10-11-20-17(14-15)22(13-7-12-21(2)3)16-8-5-6-9-19(16)24-20;/h5-6,8-11,14H,4,7,12-13H2,1-3H3;1H

InChI key

ZFWVWZODBGTOIL-UHFFFAOYSA-N

Gene Information

human ... DRD2(1813)

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Biochem/physiol Actions

Phenothiazine antipsychotic; D2 dopamine receptor antagonist.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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E A Dewey et al.
The Cornell veterinarian, 74(1), 38-49 (1984-01-01)
The metabolism of propionylpromazine in the horse was studied. Although propionylpromazine is not currently approved or recommended for use in horses, it has been used illegally to alter their performance. Propionylpromazine hydrochloride was administered intramuscularly at clinical and subclinical doses.
Thomas M Primus et al.
Pest management science, 61(6), 605-611 (2005-01-26)
An analytical method to evaluate propionylpromazine hydrochloride (PPZHCl) in tranquilizer formulations was developed using high-performance liquid chromatography (HPLC). During analysis of aged quality-control samples, a previously unreported chromatographic response was observed at a shorter retention time than PPZHCl. Further investigation
M N Mgasa et al.
Zentralblatt fur Veterinarmedizin. Reihe A, 36(3), 225-229 (1989-03-01)
Eighteen dogs of Tanzanian breeds divided into three groups of 6 were anaesthetized using either azaperone-metomidate (2 mg/kg, i.m. and 10 mg/kg i.p., respectively), propionyl promazine-xylazine-metomidate (2 mg/kg i.m., 1 mg/kg i.m. and 10 mg/kg i.p., respectively), or xylazine-ketamine (1
D Wrońska et al.
Endokrynologia Polska, 42(4), 567-574 (1991-01-01)
The study was aimed at the evaluation of propiopromazine (Combelen, Bayer), a derivative of phenothiazine, as an agent lowering in sheep the response to stress. The stress of emotional origin was induced in sheep by the isolation from herd lasting
F Gasthuys et al.
Veterinary research communications, 14(4), 309-327 (1990-01-01)
The cardiovascular changes induced by several sedatives were investigated in five ponies with a subcutaneously transposed carotid artery by means of cardiac output determinations (thermodilution technique), systemic and pulmonary artery pressure measurements (direct intravascular method) and arterial blood analysis (blood

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