M5005

Manganese(II) chloride tetrahydrate

BioReagent, suitable for insect cell culture

• Synonym(s): Manganese chloride hydrate, Manganese chloride tetrahydrate, MnCl₂.4H₂O
• Linear Formula: MnCl₂ · 4H₂O
• CAS Number: 13446-34-9
• Molecular Weight: 197.91
• EC Number: 231-869-6
• MDL number: MFCD00149792
• UNSPSC Code: 12352207
• PubChem Substance ID: 24896966
• NACRES: NA.28
• Assay: ≥99% (by AgNO₃, titration)

Properties

• product line: BioReagent
• Quality Level: 200
• Assay: ≥99% (by AgNO₃, titration)
• technique(s): cell culture | insect: suitable
• mp: 58 °C (lit.)
• SMILES string: Cl[Mn]Cl.[H]O[H].[H]O[H].[H]O[H].[H]O[H]
• InChI: 1S/2ClH.Mn.4H2O/h2*1H;;4*1H2/q;;+2;;;;/p-2
• InChI key: CNFDGXZLMLFIJV-UHFFFAOYSA-L

Description

Application

Manganese(II) chloride tetrahydrate has been used:

• as trace element in the fungal complete medium[1]
• as a supplement in the culture medium for cochlear organotypic culture[2][3]
• to determine its in vivo antiviral activity against herpes simplex virus-1 (HSV-1), vesicular stomatitis virus (VSV) and vaccinia virus in mice[4]

Biochem/physiol Actions

Manganese is an essential and one of the abundant metal in the tissues of mammals. It plays a key role in the physiological process like development, neuronal function, immune regulation, reproduction, and antioxidant defences. It functions as a cofactor and regulates the activity of the enzymes like oxido-reductases, isomerases, transferases, ligases, lyases and hydrolases It is involved in the innate immunity against viruses.[4]

Safety Information

• Pictograms: GHS06,GHS08,GHS05
• Signal Word: Danger
• Hazard Statements: H301,H318,H373
• Precautionary Statements: P260 - P264 - P280 - P301 + P310 - P305 + P351 + P338 - P314
• Hazard Classifications: Acute Tox. 3 Oral - Eye Dam. 1 - STOT RE 2
• Target Organs: Brain
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 2
• Flash Point(F): does not flash
• Flash Point(C): does not flash
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves