Skip to Content
Merck
All Photos(1)

Documents

M218

Sigma-Aldrich

Monoclonal Anti-Nicotinic Acetylcholine Receptor (α4 Subunit) antibody produced in rat

~1 mg/mL, clone mAb 299, purified immunoglobulin, buffered aqueous solution

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

MDL number:
MFCD00677279
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rat

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

mAb 299, monoclonal

form

buffered aqueous solution

species reactivity

human, chicken, rat

concentration

~1 mg/mL

technique(s)

immunohistochemistry (frozen sections): 1:800
radioimmunoassay: suitable

isotype

IgG1

UniProt accession no.

P43681

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CHRNA4(1137)
rat ... Chrna4(25590)

Specificity

Binds to native and denatured α4 AchR. May be used to quantitate α4 AchR′s on the cell surface. The epitope is located on the extracellular surface of the α4 subunit of the AchR.

Immunogen

nicotinic acetylcholine receptor (AchR) from the rat brain.

Physical form

Solution in 20 mM Na3PO4, pH 7.2, containing 150 mM NaCl and 0.05% sodium azide.

Legal Information

Sold with permission of the Salk Institute

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

V V Pollock et al.
Neuroscience, 158(4), 1311-1325 (2008-12-23)
Neuronal nicotinic receptor alpha4 subunits associated with nicotinic alpha4beta2 receptors are phosphorylated by cyclic AMP-dependent protein kinase (PKA) and protein kinase C (PKC), but the stages of receptor formation during which phosphorylation occurs and the functional consequences of kinase activation

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service