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About This Item
Empirical Formula (Hill Notation):
C6H14N2O · HCl
CAS Number:
Molecular Weight:
166.65
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Assay
≥98% (TLC)
form
powder
color
white
SMILES string
Cl.CC(C)CC(N)C(N)=O
InChI
1S/C6H14N2O.ClH/c1-4(2)3-5(7)6(8)9;/h4-5H,3,7H2,1-2H3,(H2,8,9);1H
InChI key
VSPSRRBIXFUMOU-UHFFFAOYSA-N
Biochem/physiol Actions
DL-Leucinamide hydrochloride is a racemic mixture of D- and L- enantiomers of leucinamide. Leucinamide is an amide derivative of leucine found at the C-terminal of various peptides such as the PAR-2 activating peptide SLIGRL-NH(2).
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Hidenobu Komeda et al.
Applied microbiology and biotechnology, 70(4), 412-421 (2005-07-08)
Brevundimonas diminuta TPU 5720 produces an amidase acting L-stereoselectively on phenylalaninamide. The enzyme (LaaA(Bd)) was purified to electrophoretic homogeneity by ammonium sulfate fractionation and four steps of column chromatography. The final preparation gave a single band on SDS-PAGE with a
Yasuhiko Hashida et al.
Journal of biochemistry, 141(6), 879-888 (2007-04-05)
Thermolysin activity in the hydrolysis of N-[3-(2-furyl)acryloyl]-glycyl-l-leucine amide (FAGLA) and FA-l-leucyl-l-alanine amide (FALAA) was examined at various Co(2+) and Ca(2+) concentrations. It decreased to 28% with increasing [Co(2+)] up to 18 mM. The Co(2+)-dependent inactivation was in part suppressed by
R Pacheco et al.
Analytical biochemistry, 346(1), 49-58 (2005-09-28)
This study demonstrates the use of Fourier transform infrared (FTIR) spectroscopy for monitoring both synthesis and hydrolysis reactions catalyzed by a recombinant amidase (EC 3.5.1.4) from Pseudomonas aeruginosa. The kinetics of hydrolysis of acetamide, propionamide, butyramide, acrylamide, benzamide, phenylalaninamide, alaninamide
Deepak K Bhatt et al.
Headache, 50(6), 1017-1030 (2010-05-22)
The goal of this study was to determine the vascular effects of protease-activated receptor-2 (PAR-2) activation in the rat cranial vasculature. The role of PAR-2 in pain and inflammatory conditions has been established but the information available on its effects
Formation of diastereomeric derivatives of 2-arylpropionic acids using L-leucinamide: lack of generality.
R Mehvar et al.
Journal of chromatography, 431(1), 228-230 (1988-09-23)
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