L7418

LAAM hydrochloride

≥98% (HPLC), solid

• Synonym(s): α-1-Acetylmethadol hydrochloride, (αS)-β-[(2S)-2-(Dimethylamino)propyl]-α-ethyl-β-phenyl-benzeneethanol acetate (ester) hydrochloride hydrochloride, Levomethadyl acetate hydrochloride, MK-790 hydrochloride, ORLAAM hydrochloride
• Empirical Formula (Hill Notation): C₂₃H₃₂ClNO₂
• CAS Number: 43033-72-3
• Molecular Weight: 389.96
• MDL number: MFCD01723736
• UNSPSC Code: 12352202
• PubChem Substance ID: 329817651

Properties

• Assay: ≥98% (HPLC)
• form: solid
• drug control: USDEA Schedule II; kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada
• color: white
• solubility: H₂O: >5 mg/mL
• storage temp.: 2-8°C
• SMILES string: Cl.CC[C@H](OC(C)=O)C(C[C@H](C)N(C)C)(c1ccccc1)c2ccccc2
• InChI: 1S/C23H31NO2.ClH/c1-6-22(26-19(3)25)23(17-18(2)24(4)5,20-13-9-7-10-14-20)21-15-11-8-12-16-21;/h7-16,18,22H,6,17H2,1-5H3;1H/t18-,22-;/m0./s1
• InChI key: UXBPQRGCVJOTNT-COBSGTNCSA-N
• Gene Information: human ... OPRM1(4988)

Description

Biochem/physiol Actions

LAAM hydrochloride is μ opioid receptor agonist. LAAM hydrochloride is a DEA-controlled substance, which has a slow onset, but a long duration of action. LAAM is a useful tool for studying opiate tolerance and cross-reactivity with other μ opioid receptor agonists.

Other Notes

DEA Schedule II

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H300,H315,H319,H335,H413
• Precautionary Statements: P261 - P264 - P301 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Oral - Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves