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C8289

Sigma-Aldrich

Clebopride maleate salt

~95%

Synonym(s):

4-(4-Amino-5-chloro-2-methoxybenzamido)-1-benzylpiperidine

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About This Item

Empirical Formula (Hill Notation):
C20H24ClN3O2 · C4H4O4
CAS Number:
84370-95-6
Molecular Weight:
489.95
MDL number:
MFCD00079080
UNSPSC Code:
51101500
PubChem Substance ID:
24893045

Assay

~95%

storage temp.

2-8°C

SMILES string

OC(=O)\C=C\C(O)=O.COc1cc(N)c(Cl)cc1C(=O)NC2CCN(CC2)Cc3ccccc3

InChI

1S/C20H24ClN3O2.C4H4O4/c1-26-19-12-18(22)17(21)11-16(19)20(25)23-15-7-9-24(10-8-15)13-14-5-3-2-4-6-14;5-3(6)1-2-4(7)8/h2-6,11-12,15H,7-10,13,22H2,1H3,(H,23,25);1-2H,(H,5,6)(H,7,8)/b;2-1+

InChI key

BCVIWCRZYPHHMQ-WLHGVMLRSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ki-Suk Kim et al.
International journal of toxicology, 26(1), 25-31 (2007-03-17)
The inhibition of the potassium current I(Kr) and QT prolongation has been known to be associated with drug-induced torsades de pointes arrhythmias (TdP) and sudden cardiac death. In this study, the authors investigated the cardiac electrophysiological effects of clebopride, a
Hemi-restless legs syndrome induced by clebopride.
R Erro et al.
European journal of neurology, 19(6), e59-e59 (2012-05-15)
Zhirong Tan et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(23), 2072-2076 (2010-07-06)
A sensitive and specific liquid chromatography-electrospray ionization-mass spectrometry (LC-ESI-MS/MS) method has been developed and validated for the identification and quantification of clebopride in human plasma using itopride as an internal standard. The method involves a simple liquid-liquid extraction. The analytes
I S Stovolosov et al.
Bulletin of experimental biology and medicine, 150(3), 281-285 (2011-01-18)
Administration of D(2) receptor antagonist clebopride in a dose not affecting locomotor activity was followed by a decrease in maternal bonding behavior of 10-day-old and 15-day-old albino rat pups. D(1) receptor antagonist SCH23390 had a stimulatory effect only on the
R Cuena Boy et al.
Atencion primaria, 21(5), 289-295 (1998-06-03)
To clarify if there is any basis for the hypothesis that Clebopride leads to more extrapyramidal reactions than Metoclopramide. Observational, longitudinal, retrospective and comparative study of two series of cases. The entire Spanish healthcare system. Those notified to the Spanish
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