C2650
5-Cholenic acid-3β-ol
≥98%
Synonym(s):
3β-Hydroxy-5-cholen-24-oic acid
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About This Item
Empirical Formula (Hill Notation):
C24H38O3
CAS Number:
Molecular Weight:
374.56
MDL number:
UNSPSC Code:
12352211
PubChem Substance ID:
Recommended Products
Assay
≥98%
SMILES string
C[C@@H](CCC(O)=O)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C
InChI
1S/C24H38O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h5,15,17-21,25H,4,6-14H2,1-3H3,(H,26,27)
InChI key
HIAJCGFYHIANNA-UHFFFAOYSA-N
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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J Zhang et al.
The Biochemical journal, 322 ( Pt 1), 175-184 (1997-02-15)
The metabolism of 27-, 25- and 24-hydroxycholesterol in cultures of rat astrocytes, Schwann cells and neurons was studied. 27- and 25-Hydroxycholesterol, but not 24-hydroxycholesterol, underwent 7 alpha-hydroxylation with subsequent oxidation to 7 alpha-hydroxy-3-oxo-delta 4 steroids in all three cell types.
R Hall et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2(2), 152-156 (1988-02-01)
The regulation of bile acid synthesis was studied in rabbits after interruption of the enterohepatic circulation by choledochoureteral anastomosis. Total daily bile acid output was 772 +/- 130 (SD) mumol/24 h, of which greater than 95% was glycocholic acid. Administration
A B Reiss et al.
Journal of lipid research, 35(6), 1026-1030 (1994-06-01)
Sterol 27-hydroxylase activity in bovine aortic endothelial (BAE) cells in culture has been compared with that in HepG2 cells and in Chinese hamster ovary (CHO) cells using identical culture conditions. The total enzyme activity of BAE cells (3.0 nmol/72 h
S K Krisans et al.
Journal of lipid research, 26(11), 1324-1332 (1985-11-01)
Rat liver peroxisomes have been found to oxidize 26-hydroxycholesterol, the product of cholesterol C-26 hydroxylation to 3 beta-hydroxy-5-cholenoic acid. Peroxisomes were purified by differential and equilibrium density centrifugation in a steep linear metrizamide gradient to greater than 95% purity. Purity
Y Tazawa et al.
Acta paediatrica Scandinavica, 71(1), 91-95 (1982-01-01)
Using an aluminum oxide column, we fractionated and quantitatively determined urinary monohydroxy bile acids in young infants. For comparison purposes, monohydroxy bile acids were also measured in urine from older children and adults with obstructive jaundice. Lithocholic acid was not
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