Y0000429
Trospium chloride
European Pharmacopoeia (EP) Reference Standard
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About This Item
Empirical Formula (Hill Notation):
C25H30ClNO3
CAS Number:
Molecular Weight:
427.96
UNSPSC Code:
41116107
NACRES:
NA.24
Recommended Products
grade
pharmaceutical primary standard
API family
trospium
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
InChI
1S/C25H30NO3.ClH/c27-24(25(28,19-9-3-1-4-10-19)20-11-5-2-6-12-20)29-23-17-21-13-14-22(18-23)26(21)15-7-8-16-26;/h1-6,9-12,21-23,28H,7-8,13-18H2;1H/q+1;/p-1
InChI key
RVCSYOQWLPPAOA-UHFFFAOYSA-M
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Trospium chloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
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Elizabeth J Geller et al.
Clinical drug investigation, 32(10), 697-705 (2012-08-10)
Overactive bladder (OAB) is a common condition affecting the elderly. The mainstay of treatment for OAB is medical therapy with anticholinergics. However, adverse events have been reported with this class of drugs, including cognitive changes. The objective of this study
Michael G Oefelein et al.
Clinical drug investigation, 33(2), 123-131 (2013-01-18)
Overactive bladder (OAB) is often associated with a number of co-morbid medical conditions, including diabetes mellitus. This may necessitate several concomitant treatments, thus creating the potential for drug-drug interactions (DDIs). Trospium is renally eliminated, not metabolized via cytochrome P450; therefore
M Haupt et al.
Journal of controlled release : official journal of the Controlled Release Society, 170(2), 161-166 (2013-06-05)
The overactive bladder (OAB) is a common disease with an overactivity of the detrusor muscle in the bladder wall. Besides peroral administration of anticholinergic drugs and bladder irrigations, there is a need for a sustained release formulation in the urinary
Serap Kaya et al.
Clinical rehabilitation, 25(4), 327-338 (2010-10-15)
To investigate and compare the effectiveness of various treatment protocols for the treatment of women with idiopathic detrusor overactivity. Prospective, randomized controlled trial. Departments of Physiotherapy and Rehabilitation and Obstetrics and Gynaecology, Hacettepe University. Forty-six subjects were randomized to three
Norman R Zinner et al.
Neurourology and urodynamics, 30(7), 1214-1219 (2011-04-05)
Once-daily extended-release (XR) trospium chloride has been evaluated for the treatment of overactive bladder syndrome (OAB) in two 12-week randomized, double-blind, placebo-controlled studies. This pooled analysis of the 9-month open-label extensions to these studies evaluated the long-term efficacy and tolerability
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