Skip to Content
Merck
All Photos(1)

Key Documents

81148

Sigma-Aldrich

Polyadenylic acid · Polyuridylic acid potassium salt

free from low molecular weight nucleotides, lyophilized

Synonym(s):

Poly(A) · Poly(U) potassium salt

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

CAS Number:
24936-38-7
MDL number:
MFCD00149034
UNSPSC Code:
41106305

form

powder

quality

lyophilized

mol wt

Mr 5 × 105-16.5 × 106 (5x105-16.5x106; broad molecular weight distribution)
Mr ~8500000

storage temp.

−20°C

InChI

1S/C10H14N5O7P.C9H13N2O9P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20;12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,10-;4-,6-,7-,8-/m11/s1

InChI key

VGQHQOKIMNKUEF-ZLOOHWKQSA-N

Other Notes

base ratio A:U = 1:1
RNA duplex. Useful for studying the area of attachment of nucleic acid mapping reagents: e.g. ethidium[1]; DAPI[2]; methidiumpropyl-EDTA[3]

Quantity

≥20 A260/mg

replaced by

Product No.
Description
Pricing

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Y Babayan et al.
Nucleic acids research, 15(14), 5803-5812 (1987-07-24)
Base specificity in the interaction of ethidium with double stranded synthetic RNA homopolymers has been studied by means of spectroscopic (UV-visible absorption and fluorescence), microcalorimetric and dilatometric techniques. The results show a strong base specificity in this interaction, the association
G Manzini et al.
Nucleic acids research, 13(24), 8955-8967 (1985-12-20)
The interaction of DAPI with natural and synthetic double-stranded polyribonucleotides was studied with different optical and calorimetric methods. The results were similar to those obtained previously with double-stranded polydeoxynucleotides, i.e. two interaction modes, the first of which shows high affinity
A A Bogdanov et al.
Biofizika, 53(5), 740-743 (2008-10-29)
On the basis of molecular biophysics, a methodology for the analysis of intramolecular structural order of the polynucleotide duplex poly(A).poly(U) has been developed. It was shown that the combination of circular dichroism spectroscopy with differential scanning calorimetry is an optimal
A A Ghazaryan et al.
Journal of biomolecular structure & dynamics, 24(1), 67-74 (2006-06-20)
We employed UV light absorption and circular dichroism (CD) spectroscopic measurements to study the binding of novel water-soluble porphyrins meso-tetra-(4N-allylpyridyl)porphyrin [TAlPyP4], and its Ag containing derivative to the poly(rA)poly(rU) and poly(rI)poly(rC) RNA duplexes. Our results suggest that TAlPyP4 associate with
Nathan W Luedtke et al.
Biochemistry, 42(39), 11391-11403 (2003-10-01)
Semisynthetic aminoglycoside derivatives may provide a means to selectively target viral RNA sites, including the HIV-1 Rev response element (RRE). The design, synthesis, and evaluation of derivatives based upon neomycin B, kanamycin A, and tobramycin conjugates of 9-aminoacridine are presented.
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service