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43791

Sigma-Aldrich

2,2′-Dithiodipyridine

≥99.0% (GC)

Synonym(s):

2,2′-Dipyridyl disulfide

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About This Item

Empirical Formula (Hill Notation):
C10H8N2S2
CAS Number:
2127-03-9
Molecular Weight:
220.31
Beilstein:
154629
EC Number:
218-343-1
MDL number:
MFCD00006287
UNSPSC Code:
12352112
PubChem Substance ID:
329756400
NACRES:
NA.25
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Quality Level

200

Assay

≥99.0% (GC)

form

solid

mp

56-58 °C (lit.)
57-59 °C

storage temp.

2-8°C

SMILES string

S(Sc1ccccn1)c2ccccn2

InChI

1S/C10H8N2S2/c1-3-7-11-9(5-1)13-14-10-6-2-4-8-12-10/h1-8H

InChI key

HAXFWIACAGNFHA-UHFFFAOYSA-N

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Other Notes

For the determination of sulfhydryl groups in biological materials[1]

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK8057
BCCK7442
BCBP0559V
BCBL4204V

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Determination of sulfhydryl groups with 2,2'- or 4,4'-dithiodipyridine.
D R Grassetti et al.
Archives of biochemistry and biophysics, 119(1), 41-49 (1967-03-01)
Zita Hertelendi et al.
Antioxidants & redox signaling, 10(7), 1175-1184 (2008-03-12)
This study sought to characterize the relation between the oxidation of protein sulfhydryl (SH) groups and Ca2+-activated force production in the human myocardium. Triton-permeabilized left ventricular cardiomyocytes from donor hearts were exposed to an oxidative (2,2'-dithiodipyridine, DTDP) agent in vitro
Karlhans F Che et al.
European journal of immunology, 40(8), 2248-2258 (2010-05-11)
Priming of T cells in lymphoid tissues of HIV-infected individuals occurs in the presence of HIV-1. DC in this milieu activate T cells and disseminate HIV-1 to newly activated T cells, the outcome of which may have serious implications in
Rachel L Sabado et al.
European journal of immunology, 37(7), 1752-1763 (2007-05-31)
The outcome following HIV infection depends on the nature and durability of the HIV-specific T cell response induced initially. The activation of protective T cell responses depends upon dendritic cells (DC), antigen-presenting cells which have the capacity to process and
Kazuhiko Mochida et al.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 149(4), 624-630 (2009-02-13)
In a previous study, we demonstrated that exposure to an antifouling biocide, copper pyrithione (CuPT), early during life induced vertebral deformity in the larvae of a marine fish, the mummichog (Fundulus heteroclitus). Skeletal deformities may be caused by inhibition by
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