Alternative splicing of the androgen receptor (AR) is frequently observed in castration resistant prostate cancer (CRPC). One AR isoform, the AR-V7 splice variant, is a constitutively active transcription factor which lacks a ligand binding domain and is therefore undruggable. AR-V7
Scandinavian journal of dental research, 102(4), 216-222 (1994-08-01)
The purpose of the present investigation was to determine, in patients with oral mucosal lesions of lichenoid character, whether it is possible with epicutaneous patch tests, to detect those who will react favorably to removal of amalgam. Of 48 patients
Allergic contact dermatitis due to mercury in a wedding ring and a cosmetic.
A total of 507 (M 121, F 386) cases of facial dermatitis were investigated, of whom 308 (M 49, F 259) had eczema confined to the face. The prevalence of positive patch tests was 45% (229/507). Among all the patients
Journal of toxicology. Clinical toxicology, 36(3), 233-237 (1998-07-10)
Despite their potentially disastrous side effects, topical mercury salts can still be found as ingredients in some over-the-counter preparations or local remedies. Peripheral polyneuropathy as a result of chronic ammoniated mercury poisoning was studied and followed over 2 years. A
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