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07618

Sigma-Aldrich

trans-2-Aminocyclohexanecarboxylic acid

≥97.0%

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About This Item

Empirical Formula (Hill Notation):
C7H13NO2
CAS Number:
5691-19-0
Molecular Weight:
143.18
Beilstein:
3196018
MDL number:
MFCD00145418
UNSPSC Code:
12352106
PubChem Substance ID:
329748496
NACRES:
NA.22

Quality Level

100

Assay

≥97.0%

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

color

white to faint beige

mp

~255 °C (dec.)

application(s)

peptide synthesis

SMILES string

N[C@@H]1CCCC[C@H]1C(O)=O

InChI

1S/C7H13NO2/c8-6-4-2-1-3-5(6)7(9)10/h5-6H,1-4,8H2,(H,9,10)/t5-,6-/m1/s1

InChI key

USQHEVWOPJDAAX-PHDIDXHHSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCBP3621V

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William C Pomerantz et al.
Journal of the American Chemical Society, 133(34), 13604-13613 (2011-08-06)
We have examined the effect of β-peptide modifications on the propensity of these helical molecules to form lyotropic liquid crystalline (LC) phases in water. All of the β-peptides we have examined contain 10 residues. In each case, at least three
Ulf Strijowski et al.
Organic & biomolecular chemistry, 2(8), 1105-1109 (2004-04-06)
A series of cyclic peptides containing either cis- or trans-2-aminocyclohexane carboxylic acid as mimics for L-proline has been synthesized and their structural properties have been investigated using NMR and MD methods.
Nóra V Nagy et al.
Inorganic chemistry, 51(3), 1386-1399 (2012-01-10)
With the aim of an improved understanding of the metal-complexation properties of alicyclic β-amino acid stereoisomers, and their peptides, the complex equilibria and modes of coordination with copper(II) of L-phenylalanine (F) derivatives of cis/trans-2-aminocyclohexanecarboxylic acid (c/tACHC), i.e. the dipeptides F-c/tACHC
D H Appella et al.
Nature, 387(6631), 381-384 (1997-05-22)
Proteins and RNA are unique among known polymers in their ability to adopt compact and well-defined folding patterns. These two biopolymers can perform complex chemical operations such as catalysis and highly selective recognition, and these functions are linked to folding
Arpád Balázs et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 15(30), 7376-7381 (2009-06-25)
The Pd(II)-catalyzed intramolecular oxidative cyclization of tosyl-protected cis- and trans-N-allyl-2-aminocyclohexanecarboxamides was examined, and efficient syntheses of cyclohexane-fused pyrimidin-4-ones and 1,5-diazocin-6-ones were developed. In the course of the research, a marked solvent effect was observed on both the regio- and diastereoselectivity.
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