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03755

Sigma-Aldrich

(S)-2-Fmoc-1,2,3,4-tetrahydronorharmane-3-carboxylic acid

≥98.0%

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About This Item

Empirical Formula (Hill Notation):
C27H22N2O4
CAS Number:
204322-23-6
Molecular Weight:
438.47
MDL number:
MFCD00673786
UNSPSC Code:
12352200
PubChem Substance ID:
329747796

Assay

≥98.0%

optical activity

[α]20/D +56±2°, c = 1% in DMF

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

SMILES string

OC(=O)[C@@H]1Cc2c(CN1C(=O)OCC3c4ccccc4-c5ccccc35)[nH]c6ccccc26

InChI

1S/C27H22N2O4/c30-26(31)25-13-21-20-11-5-6-12-23(20)28-24(21)14-29(25)27(32)33-15-22-18-9-3-1-7-16(18)17-8-2-4-10-19(17)22/h1-12,22,25,28H,13-15H2,(H,30,31)/t25-/m0/s1

InChI key

IHHULIKSMJSELI-VWLOTQADSA-N

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Lot/Batch Number
422046/1

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S M Paranjape et al.
Genes & development, 9(16), 1978-1991 (1995-08-15)
We have examined the effect of HMG17 on transcription by RNA polymerase II by the assembly and analysis of HMG17-containing chromatin templates consisting of regularly spaced nucleosomal arrays. Structural analysis of the chromatin indicated that HMG17 is incorporated into chromatin
Priya Prasad et al.
Frontiers in microbiology, 10, 1303-1303 (2019-06-30)
Chromatin architecture influences gene expression and makes specialized chromatin domains. Factors including histone variants, histone modifiers and chromatin remodelers that define chromatin architecture impact chromosome related processes in Candida albicans. In this context, we sought to investigate the roles of
B S Emswiler-Rose et al.
Applied and environmental microbiology, 40(1), 13-18 (1980-07-01)
Staphylococcal food poisoning associated with fermented sausages has been a recurring problem. By testing for thermonuclease by direct application of sausage casing disks on the surface of thermonuclease assay agar plates, possible Staphylococcus aureus growth in fermented sausages could be
Paul R Mueller et al.
Methods in molecular biology (Clifton, N.J.), 296, 299-328 (2004-12-04)
The Wee kinases (Wee1, Wee2, and Myt1) are major regulators of mitotic entry. They function by phosphorylating Cdc2 and related Cdks on conserved tyrosine and threonine residues. This phosphorylation blocks the activity of the Cdc2 and prevents entry into mitosis.
R T Kamakaka et al.
Genes & development, 7(9), 1779-1795 (1993-09-01)
Purified, reconstituted chromatin templates containing regular, physiological nucleosome spacing were transcribed in vitro by RNA polymerase II along with the Gal4-VP16 activator. When Gal4-VP16 was prebound to DNA before reconstitution of either H1-deficient or H1-containing chromatin, the resulting templates were

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