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Sigma-Aldrich

Tetrahydrofuran

≥99.7% (GC), contains no stabilizer, suitable for HPLC

Synonym(s):

THF, Butylene oxide, Oxolane, Tetramethylene oxide

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About This Item

Empirical Formula (Hill Notation):
C4H8O
CAS Number:
Molecular Weight:
72.11
Beilstein:
102391
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:

product name

Tetrahydrofuran, suitable for HPLC, contains no stabilizer

vapor density

2.5 (vs air)

vapor pressure

114 mmHg ( 15 °C)
143 mmHg ( 20 °C)

Assay

≥99.7% (GC)

form

liquid

autoignition temp.

610 °F

does not contain

stabilizer

expl. lim.

1.8-11.8 %

availability

available only in Japan

technique(s)

HPLC: suitable

refractive index

n20/D 1.407 (lit.)

pH

~7

bp

65-67 °C (lit.)

mp

−108 °C (lit.)

density

0.889 g/mL at 25 °C (lit.)

SMILES string

C1CCOC1

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2

InChI key

WYURNTSHIVDZCO-UHFFFAOYSA-N

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Application


  • Complexation and disproportionation of group 4 metal (alkoxy) halides with phosphine oxides.: This research utilizes tetrahydrofuran (THF) as a solvent to study the complexation and disproportionation reactions of group 4 metal halides, providing insights into coordination chemistry and potential applications in materials science (Seno et al., 2024).

  • Synthesis of Room Temperature Curable Polymer Binder Mixed with Polymethyl Methacrylate and Urethane Acrylate for High-Strength and Improved Transparency.: THF is used as a solvent in the synthesis of advanced polymer binders, highlighting its role in developing materials with enhanced mechanical properties and optical clarity for industrial applications (Lee et al., 2024).

  • Fabrication of Polypyrrole Hollow Nanospheres by Hard-Template Method for Supercapacitor Electrode Material.: This study employs THF in the fabrication process of polypyrrole nanospheres, demonstrating its importance in the production of high-performance supercapacitor electrode materials (Hong et al., 2024).

  • Promoting Cross-Link Reaction of Polymers by the Matrix-Filler Interface Effect: Role of Coupling Agents and Intermediate Linkers.: The use of THF as a solvent facilitates the cross-linking reactions in polymers, enhancing their mechanical stability and expanding their applications in various fields of materials science (Huang et al., 2024).

  • Solvent Regulation Induced Cathode Aggregation-Induced Electrochemiluminescence of Tetraphenylethylene Nanoaggregates for Ultrasensitive Zearalenone Analysis.: THF is critical in the solvent regulation process for electrochemiluminescence assays, significantly improving the sensitivity of analytical techniques for detecting environmental contaminants (Chen et al., 2024).

recommended

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system, Respiratory system

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

5.9 °F

Flash Point(C)

-14.5 °C


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We present total, elastic, and inelastic cross sections for positron and electron scattering from tetrahydrofuran (THF) in the energy range between 1 and 5000 eV. Total cross sections (TCS), positronium formation cross sections, the summed inelastic integral cross sections (ICS)
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