14-817-M

Met (M1268T) Protein, active, 10 µg

• UNSPSC Code: 12352202
• eCl@ss: 32160405
• NACRES: NA.32

Properties

• biological source: human
• Quality Level: 100; 300
• mol wt: M_w 50.1 kDa
• manufacturer/tradename: Upstate^®
• technique(s): activity assay: suitable (kinase)
• NCBI accession no.: J02958
• UniProt accession no.: P08581

Description

General description

Met M1268T is a somatic mutation that has been identified in patients with papillary renal carcinomas (HPRC). In vitro studies have demonstrated enhanced kinase activity from this mutant.

N-terminal 6His-tagged, recombinant, human, Met amino acids 974-end, containing the mutation M1268T.

expressed by baculovirus in Sf21 insect cells

Application

Active, N-terminal 6His-tagged, recombinant, human, Met amino acids 974-end, containing the mutation M1268T. For use in Kinase Assays.

Biochem/physiol Actions

• Protein Target: Met
• Target Sub-Family:TK

Packaging

Available in 250 μg --call for pricing and availability and reference catalog number 14-817M when ordering the 250 μg size.

Physical form

Format: Ni²⁺/NTA-agarose

Storage and Stability

6 months at -70°C

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H317
• Precautionary Statements: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable