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1.24505

Sigma-Aldrich

Osmium(VIII) oxide

for microscopy

Synonym(s):

Osmium(VIII) oxide, Osmic acid, Osmiumtetraoxide

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About This Item

Empirical Formula (Hill Notation):
O4Os
CAS Number:
20816-12-0
Molecular Weight:
254.23
MDL number:
MFCD00011150
UNSPSC Code:
12352303
EC Index Number:
244-058-7

vapor pressure

10 hPa ( 20 °C)

Quality Level

400

form

solid

potency

15 mg/kg LD50, oral (Rat)

color

yellow

pH

6 (20 °C, 25 g/L in H2O)

bp

130 °C/1013 hPa

mp

40 °C

solubility

65 g/L

density

4.91 g/cm3 at 20 °C

bulk density

1500 kg/m3

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

15-25°C

InChI

1S/4O.Os

InChI key

VUVGYHUDAICLFK-UHFFFAOYSA-N

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General description

Osmium tetroxide for microscopy can be used to visualize unsaturated lipids. A part of the lipids is immediately blackened by the influence of osmic acid solution. The immediate black coloration results from the -C=C- double bond of the unsaturated fatty acid. The fatty acids that are made brownish at first can be blackened by treatment with 60-70% alcohol. For electron microscopy or semithin sectioning the glutardialdehyde-fixed specimens are post-fixed with osmium(VIII) oxide. Lipid inclusions appear black on a yellow to brown background. It is an IVD / CE registered product. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.

Linkage

Replaces: OX0260-5; OX0260-3

Analysis Note

Identity (Raman-spectrum): conforms

Pictograms

CorrosionSkull and crossbones
GHS05,GHS06

Signal Word

Danger

Hazard Statements

H300 + H310 + H330 - H314

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 1

Certificates of Analysis (COA)

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