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850702P

Avanti

12:0 PE

1,2-dilauroyl-sn-glycero-3-phosphoethanolamine, powder

Synonym(s):

1,2-didodecanoyl-sn-glycero-3-phosphoethanolamine; DLPE; PE(12:0/12:0)

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About This Item

Empirical Formula (Hill Notation):
C29H58NO8P
CAS Number:
59752-57-7
Molecular Weight:
579.75
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (850702P-1g)
pkg of 1 × 200 mg (850702P-200mg)
pkg of 1 × 25 mg (850702P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850702P

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O

InChI

1S/C29H58NO8P/c1-3-5-7-9-11-13-15-17-19-21-28(31)35-25-27(26-37-39(33,34)36-24-23-30)38-29(32)22-20-18-16-14-12-10-8-6-4-2/h27H,3-26,30H2,1-2H3,(H,33,34)

InChI key

ZLGYVWRJIZPQMM-UHFFFAOYSA-N

General description

Phosphatidylethanolamine (PE) is one of the widely distributed glycerophospholipid in eukaryotic cells. 1,2-dilauroyl-sn-glycero-3-phosphoethanolamine (12:0 PE/DLPE) possess an ammonium head group (RNH3+) and has alkyl chains made of 11 carbon atoms.

Application

1,2-dilauroyl-sn-glycero-3-phosphoethanolamine (12:0 PE):
  • has been used as a lipid standard in the optimization of the liquid chromatography−mass spectrometry (LC-MS) method conditions
  • may be used as a phospholipid (PL) standard to quantify phosphatidylethanolamine (PE) from plant lipids
  • may be used to prepare anionic liposomes
  • may be used to prepare binary giant unilamellar vesicles (GUVs)

Biochem/physiol Actions

Phosphatidylethanolamine (PE) plays a vital role in the structure and function of eukaryotic membranes.

Packaging

20 mL Clear Glass Screw Cap Vial (850702P-1g)
5 mL Amber Glass Screw Cap Vial (850702P-200mg)
5 mL Amber Glass Screw Cap Vial (850702P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Oligonucleotide delivery with serum into HeLa cells using polycation liposomes
Mady MM
Journal of Biomedical Materials Research. Part B, Applied Biomaterials, 7(1), 69-69 (2007)
The influence of DOPC on the permeability of lipid membrane: Detergent solubilization and NMR study
Mady MM
Romanian Journal of Biophysics, 17, 259-267 (2007)
Phosphatidylethanolamine metabolism in health and disease
International Review of Cell and Molecular Biology, 321, 29-88 (2016)
Takehiro Jimbo et al.
Biophysical journal, 110(7), 1551-1562 (2016-04-14)
We investigate a temperature-driven recursive division of binary giant unilamellar vesicles (GUVs). During the heating step of the heating-cooling cycle, the spherical mother vesicle deforms to a budded limiting shape using up the excess area produced by the chain melting
Phosphatidylethanolamine metabolism in health and disease
International Review of Cell and Molecular Biology, 321, 29-88 (2016)
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