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D196800

Sigma-Aldrich

1-Fluoro-2,4-dinitrobenzene

99%

Synonym(s):

2,4-Dinitro-1-fluorobenzene, DNFB, DNPF, FDNB, Sanger reagent

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About This Item

Linear Formula:
(O2N)2C6H3F
CAS Number:
Molecular Weight:
186.10
Beilstein:
398632
EC Number:
MDL number:
UNSPSC Code:
12352100

Assay

99%

refractive index

n20/D 1.569 (lit.)

bp

178 °C/25 mmHg (lit.)

mp

25-27 °C (lit.)

density

1.482 g/mL at 25 °C (lit.)

SMILES string

[O-][N+](=O)c1ccc(F)c(c1)[N+]([O-])=O

InChI

1S/C6H3FN2O4/c7-5-2-1-4(8(10)11)3-6(5)9(12)13/h1-3H

InChI key

LOTKRQAVGJMPNV-UHFFFAOYSA-N

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Application

Reagent for labeling terminal amino acid groups. Used in the detection of phenols. Suppresses the action potential in nerves. Induces contact hypersensitivity.

replaced by

Product No.
Description
Pricing

Pictograms

Health hazardExclamation mark

Signal Word

Warning

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 3

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

327.2 °F

Flash Point(C)

164 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Journal of Chromatography A, 44, 251-251 (1969)
W R Welches et al.
Biochemistry, 20(3), 512-517 (1981-02-03)
Bacterial luciferase catalyzes the mixed-function oxidation of a long-chain saturated aldehyde and FMNH2 to yield the carboxylic acid, FMN, and blue-green light. The enzyme was inactivated by 2,4-dinitrofluorobenzene (FDNB) with an observed second-order rate constant (k2(obsd) of 157 M-1 min-1
Suppression of the action potential in nerve by nitrobenzene derivatives.
I M Cooke et al.
Proceedings of the National Academy of Sciences of the United States of America, 60(2), 470-477 (1968-06-01)
The terminal peptides of insulin.
F SANGER
The Biochemical journal, 45(5), 563-574 (1949-01-01)

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