![Bis[tetrakis(hydroxymethyl)phosphonium] sulfate solution technical, 70-75% in H2O (T)](/deepweb/assets/sigmaaldrich/product/structures/236/818/d029a904-00ee-46ad-9fe2-2369f9894cc4/640/d029a904-00ee-46ad-9fe2-2369f9894cc4.png)
For this compound, the Tetrakis(hydroxymethyl)phosphonium ion is the cation, and the chloride ion is the anion. Since the Tetrakis(hydroxymethyl)phosphonium ion is the more "interesting" part of this compound, one might see it referred to in the chemical literature as a cationic crosslinker or a cationic ligand.
404861
Tetrakis(hydroxymethyl)phosphonium chloride solution
Tetrakis(hydroxymethyl)phosphonium chloride solution
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80% in H2O
Synonym(s):
THPC solution
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$111.00
500 ML
$326.00
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100 ML
$111.00
500 ML
$326.00
About This Item
Linear Formula:
(HOCH2)4PCl
CAS Number:
Molecular Weight:
190.56
Beilstein:
3631669
MDL number:
UNSPSC Code:
12352101
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
form
liquid
concentration
80% in H2O
refractive index
n20/D 1.512
density
1.341 g/mL at 25 °C
SMILES string
[Cl-].OC[P+](CO)(CO)CO
InChI
1S/C4H12O4P.ClH/c5-1-9(2-6,3-7)4-8;/h5-8H,1-4H2;1H/q+1;/p-1
InChI key
AKXUUJCMWZFYMV-UHFFFAOYSA-M
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Application
Tetrakis(hydroxymethyl)phosphonium chloride solution (80% in H2O) has been used as a reducing agent and stabilizing ligand for the synthesis of gold nanoparticles (AuNPs) from gold(III) chloride trihydrate (HAuCl4.3H2O).[1][2] It is a tetra-functional, amine-reactive, aqueous crosslinker that can be used for tuning the properties of protein-based hydrogels for 3D cell encapsulation applications.[3]
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Met. Corr. 1 - Repr. 1B - Skin Corr. 1B - Skin Sens. 1
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Nanoscale, 3(5), 2009-2014 (2011)
Beyond gold: rediscovering tetrakis-(hydroxymethyl)-phosphonium chloride (THPC) as an effective agent for the synthesis of ultra-small noble metal nanoparticles and Pt-containing nanoalloys
Hueso J L, et al.
Royal Society of Chemistry Advances, 3(26), 10427-10433 (2013)
María Carmen Bartolomé et al.
Environmental toxicology and chemistry, 24(12), 3137-3142 (2006-02-01)
This paper reports the acute toxicity of three biocides used in the disinfection of cooling towers, tetrakis(hydroxymethyl) phosphonium chloride (THPC), trichloroisocyanuric acid (TCIC), and sodium bromide (NaBr), on Artemia larvae, their effect on the phototactic response of this organism, and
Urmimala Maitra et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 12(12), 2322-2327 (2011-07-12)
Gold nanoparticles with average diameters in the range 2.5-15 nm, prepared at the organic/aqueous interface by using tetrakis(hydroxymethyl)phosphonium chloride (THPC) as reducing agent, exhibit ferromagnetism whereby the saturation magnetization M(S) increases with decreasing diameter and varies linearly with the fraction
T H Connor et al.
Journal of environmental pathology and toxicology, 4(1), 145-158 (1980-08-01)
This study was undertaken to evaluate the mutagenicity of the flame retardant, Tetrakis (Hydroxymethyl) Phosphonium Sulfate -75% or its possible metabolic products using a battery of in vitro and in vivo assays. The starting material in the fabric treatment process
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