378704
Tropane
98%
Synonym(s):
8-Methyl-8-azabicyclo[3.2.1]octane
Sign Into View Organizational & Contract Pricing
All Photos(3)
About This Item
Empirical Formula (Hill Notation):
C8H15N
CAS Number:
Molecular Weight:
125.21
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
form:
liquid
Assay:
98%
Recommended Products
![9-Azabicyclo[3.3.1]nonane N-oxyl 95%](/deepweb/assets/sigmaaldrich/product/structures/287/155/e2f4a2e1-1d4e-4bed-9187-9e16d23cbbbf/640/e2f4a2e1-1d4e-4bed-9187-9e16d23cbbbf.png)
Assay
98%
form
liquid
refractive index
n20/D 1.477 (lit.)
bp
167-169 °C (lit.)
density
0.931 g/mL at 25 °C (lit.)
SMILES string
CN1[C@H]2CCC[C@@H]1CC2
InChI
1S/C8H15N/c1-9-7-3-2-4-8(9)6-5-7/h7-8H,2-6H2,1H3/t7-,8+
InChI key
XLRPYZSEQKXZAA-OCAPTIKFSA-N
General description
Tropane (8-methyl-8-azabicyclo[3.2.1]-octane) is a bridged bicyclic N-containing compound.[1] The 8-methyl-8-azabicyclo[3.2.1]-octane has a tropane ring system, which is an important substructure in a number of natural products and synthetic compounds of biological and medicinal importance.[2] Production of tropane alkaloid in callus and root cultures of seven Hyoscyamus species has been studied.[3] Tropane derivatives are reported to undergo rapid N-methyl inversion.[4]
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
Flash Point(F)
107.6 °F - closed cup
Flash Point(C)
42 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
A Kokotkiewicz et al.
Food chemistry, 221, 535-540 (2016-12-17)
Thin layer chromatographic methods for quantitative determination of nightshade-specific tropane (l-hyoscyamine, scopolamine) and steroidal alkaloids (α-solanine, α-chaconine) in goji berries (L. barbarum L., Solanaceae) were developed. The analysis of tropane derivatives included separation on silica gel-coated HPTLC plates using mobile
Enhancing Tropane Alkaloid Production Based on the Functional Identification of Tropine-Forming Reductase in
Kaihui Zhao et al.
Frontiers in plant science, 8, 1745-1745 (2017-11-01)
An improved synthesis of (+)-2-tropinone.
Zhang C, et al.
The Journal of Organic Chemistry, 62(22), 7888-7889 (1997)
Abigail Moreno-Pedraza et al.
Metabolites, 9(7) (2019-07-07)
different Solanaceae and Erythroxylaceae species produce tropane alkaloids. These alkaloids are the starting material in the production of different pharmaceuticals. The commercial demand for tropane alkaloids is covered by extracting them from cultivated plants. Datura stramonium is cultivated under greenhouse
Tehetena Mesganaw et al.
Organic process research & development, 18(9), 1097-1104 (2014-10-08)
A Rh-catalyzed C-H bond activation/alkenylation/electrocyclization cascade reaction provides diverse 1,2-dihydropyridines from simple and readily available precursors. The reaction can be carried out at low (<1%) Rh-catalyst loadings, and the use of the robust, air-stable Rh precatalyst, [RhCl(cod)]
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
