Journal of medicinal chemistry, 40(20), 3292-3296 (1997-11-05)
The synthesis and inhibitory activity against DNA gyrase of a series of diphenic acid monohydroxamides 4a-f are described. A protocol of two biological assays showed conclusively that inhibition occurs specifically at the DNA-DNA gyrase complex and is not attributable to
Applied and environmental microbiology, 58(6), 1832-1838 (1992-06-01)
The ligninolytic fungus Phanerochaete chrysosporium oxidized phenanthrene and phenanthrene-9,10-quinone (PQ) at their C-9 and C-10 positions to give a ring-fission product, 2,2'-diphenic acid (DPA), which was identified in chromatographic and isotope dilution experiments. DPA formation from phenanthrene was somewhat greater
Journal of pharmaceutical sciences, 76(8), 611-620 (1987-08-01)
A convenient procedure has been developed for the determination of partition and distribution coefficients. The method involves the potentiometric titration of the compound, first in water and then in a rapidly stirred mixture of water and octanol. An automatic titrator
Dalton transactions (Cambridge, England : 2003), 49(3), 817-828 (2019-12-20)
Diphenic acid (H2dip) has been used to synthesize nine homo- or heterometallic uranyl ion complexes under solvo-hydrothermal conditions. The diphenate ligand dip2- adopts different coordination modes, mixtures of κ2-O,O'-chelation by individual carboxylate groups, chelation involving both carboxylate groups, and bridging
Chemical communications (Cambridge, England), (5)(5), 643-644 (2005-01-27)
As a model for DNA damage by photodimerization of its thymine component, a new [2 + 2] photodimerization of 5-chloro and 5-methyl-2-pyridone to the corresponding cis-anti-dimers as their inclusion complexes with 1,1'-biphenyl-2,2'-dicarboxylic acid was found, and the mechanism of this
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
