ESR1
estrogen receptor 1
Synonyms:
ER, ESR, ESRA, ESTRR, Era, NR3A1
Species:
Human ESR1 (2099), Mouse Esr1 (13982), Rat Esr1 (24890), domestic cat ESR1 (552888), dog ESR1 (403640), chicken ESR1 (396099), Thale Cress ESR1 (837856), Horse ESR1 (791249), Zebrafish esr1 (259252), cow ESR1 (407238) ...More
UniProtKB ID:
Gene ID:
- Human(2099) Summary: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq, Jul 2008]
- Mouse(13982) estrogen receptor 1 (alpha)
- Rat(24890) estrogen receptor 1
- domestic cat(552888) estrogen receptor 1
- dog(403640) estrogen receptor 1
- chicken(396099) estrogen receptor 1
- Thale Cress(837856) ethylene-responsive transcription factor ESR1
- Horse(791249) estrogen receptor 1
- Zebrafish(259252) estrogen receptor 1
- cow(407238) estrogen receptor 1
- Goat(100860768) estrogen receptor 1
- sheep(443228) estrogen receptor 1
- domestic guinea pig(100713276) estrogen receptor 1
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Small Molecule - Activator
Product Number
Description
Species
Small Molecule - Agonist
Product Number
Description
Species
Ethinyl Estradiol, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Small Molecule - Allosteric Modulator
Product Number
Description
Species
Tamoxifen citrate for performance test, European Pharmacopoeia (EP) Reference Standard,
Species
human
Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ER alpha antibody, Rabbit Monoclonal, recombinant, expressed in HEK 293 cells, clone RM292, purified immunoglobulin,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-Estrogen-related Receptor α Antibody, Upstate®, from rabbit,
Species Reactivity
hamster, human, mouse, rat
Application
electrophoretic mobility shift assay
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
ChIPAb+ Estrogen Receptor α - ChIP Validated Antibody and Primer Set, ascites fluid, from mouse,
Species Reactivity
human, mouse
Application
ChIP
western blot
western blot
Anti-Estradiol Antibody, clone 6E1, ascites fluid, clone 6E1, Chemicon®,
Species Reactivity
human
Application
ELISA
Anti-phospho-ESR1 (pSer104) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Small Molecule - Ligand
Product Number
Description
Species
Small Molecule - Mixed Agonist/Antagonist
Product Number
Description
Species
Proteins
Product Number
Description
Species
Estrogen Receptor-α human, ≥80% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Species
human
PrEST Antigen ESR1, Prestige Antigens™ Powered by Atlas Antibodies, buffered aqueous solution,
Species
human
PrEST Antigen ESR1, Prestige Antigens™ Powered by Atlas Antibodies, buffered aqueous solution,
Species
human
esiRNA
Product Number
Description
Species