Generation 2 to generation 5 poly(amidoamine) (PAMAM) dendrimers having different terminal functionalities were analyzed by capillary electrophoresis (CE). Polyacrylamide gel electrophoresis was also used to assess the composition of the individual generations for comparison with the CE results. Separation of
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 60(8-9), 2181-2184 (2004-07-14)
The charge-transfer interaction of 2,3-diaminopyridine (DAPY) and iodine has been investigated spectrophotometrically in the solvents chloroform and dichloromethane at room temperature. The results indicate the formation of 1:2 charge-transfer complex in each solvent with the observation of the two characteristic
Journal of medicinal chemistry, 47(26), 6439-6442 (2004-12-14)
Bradykinin B1 receptor antagonists embody a potentially novel approach for the treatment of chronic pain and inflammation. A series of 2,3-diaminopyridine B1 antagonists was optimized to have sub-nanomolar affinity and good pharmacokinetic properties. Lead compounds were shown to exhibit good
A new voltammetric enzyme-linked immunoassay system using the electrochemical substrate 2,3-diaminopyridine (DAP) and horseradish peroxidase (HRP) system has been developed. DAP is oxidized with H2O2 catalyzed by HRP, and the resulting electroactive product produces a sensitive voltammetric peak at potential
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 75(1), 198-202 (2009-11-26)
The charge transfer (CT) interaction between iodine and 2,3-diaminopyridine (DAPY) has been thoroughly investigated via theoretical calculations. A Hartree-Fock, 3-21G level of theory was used to optimize and calculate the Mullican charge distribution scheme as well as the vibrational frequencies
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