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Di-n-butyl phthalate solution

certified reference material, 5000 μg/mL in methanol

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About This Item

CAS Number:
84-74-2
UNSPSC Code:
41116105

grade

certified reference material
TraceCERT®

Quality Level

300

product line

TraceCERT®

CofA

current certificate can be downloaded

packaging

ampule of 1 mL

concentration

5000 μg/mL in methanol

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

single component solution

storage temp.

2-8°C

InChI

1S/C16H22O4/c1-3-5-11-19-15(17)13-9-7-8-10-14(13)16(18)20-12-6-4-2/h7-10H,3-6,11-12H2,1-2H3

InChI key

DOIRQSBPFJWKBE-UHFFFAOYSA-N

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General description

Di-n-butyl phthalates (DnBPs) are mainly used in personal-care products like perfumes, aftershaves, shampoos, make up and nail products, paints, etc.

Application

DnBP has been used as a certified reference material (CRM) for the determination of the analyte in cleaning and personal care products by liquid chromatography-mass spectrometry (LC-MS) and as a reference standard for the identification of the analyte in tea beverages by ionic liquid-based hollow fiber liquid phase microextraction (IL-HF-PLME), coupled with high-performance liquid chromatography-diode array detection (HPLC-DAD). It may be used as a reference standard for the analysis of the analyte in food samples and as urinary metabolites in pregnant women by LC-MS.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.
Description
Pricing

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - Repr. 1B - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F

Flash Point(C)

9.7 °C

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH SVHC Candidate List

CAS No.

EU REACH Annex XVII (Restriction List)

CAS No.

EU REACH Annex XIV (Authorisation List)

CAS No.

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Certificates of Analysis (COA)

Lot/Batch Number
LRAD3088
LRAD0593
LRAC0988
XA14597V
XA14575V

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Determination of 12 urinary phthalate metabolites in Norwegian pregnant women by core-shell high performance liquid chromatography with on-line solid-phase extraction, column switching and tandem mass spectrometry
Sabaredzovic A, et al.
Journal of Chromatography. B, Biomedical Applications, 1002, 343-352 (2015)
Method development for the analysis of phthalate esters in tea beverages by ionic liquid hollow fibre liquid-phase microextraction and liquid chromatographic detection
Wang J, et al.
Food Control, 67, 278-284 (2016)
Determination of 23 phthalic acid esters in food by liquid chromatography tandem mass spectrometry
Xu D, et al.
Journal of Chromatography A, 1324, 49-56 (2014)
Harpreet Bhatia et al.
Environmental toxicology and chemistry, 32(10), 2335-2344 (2013-06-14)
Di-n-butyl phthalate (DnBP) is an industrial pollutant with antiandrogenic effects reported in male mammals and fish. Little research has been done on the endocrine effects of DnBP in female fish. The present study investigated the changes in ovarian histology and
Sarah Moody et al.
Endocrinology, 154(9), 3460-3475 (2013-06-15)
Phthalates are plasticizers with widespread industrial, domestic, and medical applications. Epidemiological data indicating increased incidence of testicular dysgenesis in boys exposed to phthalates in utero are reinforced by studies demonstrating that phthalates impair fetal rodent testis development. Because humans are
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