V5015

VU0152100

≥98% (HPLC)

• Synonym(s): 3-Amino-N-[(4-methoxyphenyl)methyl]-4,6-dimethyl-thieno[2,3-b]pyridine-2-carboxamide
• Empirical Formula (Hill Notation): C₁₈H₁₉N₃O₂S
• CAS Number: 409351-28-6
• Molecular Weight: 341.43
• NACRES: NA.77
• PubChem Substance ID: 329829056
• UNSPSC Code: 12352200
• MDL number: MFCD02742972
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• solubility: DMSO: >50 mg/mL
• storage temp.: 2-8°C
• SMILES string: COc1ccc(CNC(=O)c2sc3nc(C)cc(C)c3c2N)cc1
• InChI: 1S/C18H19N3O2S/c1-10-8-11(2)21-18-14(10)15(19)16(24-18)17(22)20-9-12-4-6-13(23-3)7-5-12/h4-8H,9,19H2,1-3H3,(H,20,22)
• InChI key: MDNWGCQSCGNTKH-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Positive allosteric modulator of muscarinic choline receptor M4.

Positive allosteric modulator of muscarinic choline receptor M4. Potentiates activation by acetylcholine, but posesses no intrinsic agonist activity alone.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301,H319
• pcodes: P264 - P280 - P301 + P310 - P305 + P351 + P338 - P337 + P313 - P405
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable