SRP5324
FASTK, active, GST tagged human
PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym(s):
FAST, FLJ13079
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About This Item
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biological source
human
recombinant
expressed in baculovirus infected Sf9 cells
product line
PRECISIO®
Assay
≥70% (SDS-PAGE)
form
buffered aqueous glycerol solution
specific activity
0.8-1.2 nmol/min·mg
mol wt
~84 kDa
NCBI accession no.
application(s)
cell analysis
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... FASTK(10922)
General description
FASTK or Fas-Activated Serine/Threonine Kinase is a member of the serine/threonine protein kinase family that becomes rapidly activated during Fas-mediated apoptosis in Jurkat cells and in response to Fas receptor ligation. FASTK interacts with and phosphorylates TIA1 which is an apoptosis-promoting nuclear RNA-binding protein. FAST K influences alternative pre-mRNA splicing by affecting the activity of TIA-1/TIAR. FASTK is a strong inducer of lymphocyte apoptosis. FASTK is the component of the molecular cascade that involved in FAS-mediated apoptosis. FASTK is highly expreesed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas.
Physical form
Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Preparation Note
After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.
Legal Information
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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