SML3166

Mitochonic Acid 5

≥98% (HPLC)

• Synonym(s): α-[2-(2,4-Difluorophenyl)-2-oxoethyl]-1H-indole-3-acetic acid, 4-(2,4-Difluorophenyl)-2-(1H-indol-3-yl)-4-oxobutanoic acid
• Empirical Formula (Hill Notation): C₁₈H₁₃F₂NO₃
• CAS Number: 1354707-41-7
• Molecular Weight: 329.30
• MDL number: MFCD31657404
• UNSPSC Code: 12352106
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: OC(C(CC(C1=C(F)C=C(F)C=C1)=O)C2=CNC3=CC=CC=C32)=O
• InChI: 1S/C18H13F2NO3/c19-10-5-6-12(15(20)7-10)17(22)8-13(18(23)24)14-9-21-16-4-2-1-3-11(14)16/h1-7,9,13,21H,8H2,(H,23,24)
• InChI key: BOKQALWNGNLTOC-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Mitochonic Acid 5 is a potent enhancer of mitochondrial ATP production that significantly increased the cellular ATP level in Hep3B human hepatocellular carcinoma cells. Mitochonic Acid 5 improves the survival of fibroblasts from patients with mitochondrial diseases. It appears that mitochonic Acid 5 facilitates ATP synthase oligomerization and supercomplex formation with mitofilin/Mic60.

potent enhancer of mitochondrial ATP production

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable