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SML2976

WR99210 hydrochloride

≥98% (HPLC)

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Size/SKUAvailabilityPrice
5 mg
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€ 160,00
25 mg
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€ 524,00

About This Item

Empirical Formula (Hill Notation):
C14H18Cl3N5O2 · HCl
CAS Number:
Molecular Weight:
431.14
UNSPSC Code:
51111800
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated

€ 160,00


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Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

[Cl-].Clc1c(cc(c(c1)Cl)OCCCON2C(N=C(N=C2N)N)(C)C)Cl.[H+]

InChI

1S/C14H18Cl3N5O2.ClH/c1-14(2)21-12(18)20-13(19)22(14)24-5-3-4-23-11-7-9(16)8(15)6-10(11)17;/h6-7H,3-5H2,1-2H3,(H4,18,19,20,21);1H

InChI key

VOTSDCGUYAGUNS-UHFFFAOYSA-N

Biochem/physiol Actions

Potent P. falciparum dihydrofolate reductase (pfDHFR) inhibitor.
WR99210 is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target. It has subnanomolar potency for the wild type, double mutant and quadruple mutant dihydrofolate reductases.

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This Item
WH0001719M1D6566JRD1146
description

≥98% (HPLC)

description

clone 2B10, purified immunoglobulin, buffered aqueous solution

description

≥80% (SDS-PAGE), recombinant, expressed in E. coli, ≥1 units/mg protein

description

AldrichCPR

assay

≥98% (HPLC)

assay

-

assay

≥80% (SDS-PAGE)

assay

-

form

powder

form

buffered aqueous solution

form

solution

form

solid

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-

storage condition

desiccated

storage condition

-

storage condition

-

storage condition

-

solubility

DMSO: 2 mg/mL, clear

solubility

-

solubility

-

solubility

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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