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SML2210

AubipyOMe

≥97% (NMR)

Synonym(s):

(SP-4-2)-dichloro(4,4′-dimethoxy-2,2′-bipyridine-kN1,kN1′)-Gold(1+), hexafluorophosphate(1-), [Au(4,4′-dimethoxy-2,2′-bipyridine)Cl2][PF6]

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Size/SKUAvailabilityPrice
5 mg
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€ 90,70
25 mg
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€ 369,00

About This Item

Empirical Formula (Hill Notation):
C12H12AuCl2N2O2 · PF6
CAS Number:
Molecular Weight:
629.07
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥97% (NMR)
Form:
powder

€ 90,70


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assay

≥97% (NMR)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

[Cl-][Au+3]1([N]2=C(C=C(C=C2)OC)C3=[N]1C=CC(OC)=C3)[Cl-].F[P-](F)(F)(F)(F)F

Biochem/physiol Actions

AubipyOMe is a potent inhibitor of tartrate resistant acid phosphatase (TRAP/ACP5), a metalloenzyme expressed in activated osteoclasts and in macrophages. AubipyOMe exhibited IC50 values of 1.3 μM for TRAP5a and 1.8 μM for TRAP5b and inhibited TRAP activity in murine macrophage and human lung tissue extracts.
Tartrate resistant acid phosphatase (TRAP/ACP5) inhibitor

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description

≥97% (NMR)

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≥98% (HPLC)

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clone 2D9, purified immunoglobulin, buffered aqueous solution

description

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

form

powder

form

powder

form

buffered aqueous solution

form

buffered aqueous glycerol solution

assay

≥97% (NMR)

assay

≥98% (HPLC)

assay

-

assay

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

-

solubility

-

color

white to beige

color

white to beige

color

-

color

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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