SML1111

S 24795

≥98% (HPLC)

• Synonym(s): 2-[2-(4-Bromophenyl)-2-oxoethyl]-1-methyl pyridinium iodide
• Empirical Formula (Hill Notation): C₁₄H₁₃BrNO · I
• CAS Number: 304679-75-2
• Molecular Weight: 418.07
• MDL number: MFCD18086873
• UNSPSC Code: 12352202
• PubChem Substance ID: 329825652
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• color: white to light brown
• solubility: H₂O: 1 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: C[N+](C=CC=C1)=C1CC(C2=CC=C(Br)C=C2)=O.[I-]
• InChI: 1S/C14H13BrNO.HI/c1-16-9-3-2-4-13(16)10-14(17)11-5-7-12(15)8-6-11;/h2-9H,10H2,1H3;1H/q+1;/p-1
• InChI key: LERUHBBUGAOYOD-UHFFFAOYSA-M

Description

Biochem/physiol Actions

S 24795 is a selective partial agonist for the α7-subtype of nicotinic acetylcholine receptor (nAChR). S 24795 was shown to be effective at improving learning and memory in various animal models relevant to Alzheimer′s disease and age-related memory loss, and is used in investigating the roles of α7 nAChRs in aging, learning, memory, and cognition.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable