SML0876
Filastatin
≥98% (HPLC)
Synonym(s):
(3-Chloro-4-methylphenyl)[4-(4-nitrophenyl)-1-piperazinyl]-methanone
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| Size/SKU | Availability | Price |
|---|---|---|
25 mg | Check Cart for Availability | € 252,00 |
About This Item
Empirical Formula (Hill Notation):
C18H18ClN3O3
CAS Number:
Molecular Weight:
359.81
UNSPSC Code:
51111800
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 15 mg/mL, clear
storage temp.
2-8°C
SMILES string
Clc1c(ccc(c1)C(=O)N2CCN(CC2)c3ccc(cc3)[N+](=O)[O-])C
InChI
1S/C18H18ClN3O3/c1-13-2-3-14(12-17(13)19)18(23)21-10-8-20(9-11-21)15-4-6-16(7-5-15)22(24)25/h2-7,12H,8-11H2,1H3
InChI key
PNECWWUOUHGWQG-UHFFFAOYSA-N
Biochem/physiol Actions
Filastatin blocks the ability of Candida albicans, and other Candida sp. to bind to polystyrene, and human A549 cell monolayers. Filastatin also blocks biofilm formation and yeast-to-hyphal morphologic transition through inhibition of the hyphal-specific promoter HWP1.
Filastatin is an inhibitor of Candida albicans surface binding, morphology transition and biofilm formation.
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This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥50% (HPLC) | description AldrichCPR | description AldrichCPR |
| form powder | form solid | form - | form - |
| assay ≥98% (HPLC) | assay - | assay - | assay - |
| Quality Level 100 | Quality Level - | Quality Level - | Quality Level - |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. - | storage temp. - |
| solubility DMSO: 15 mg/mL, clear | solubility DMSO: 1 mg/mL | solubility - | solubility - |
| color white to beige | color - | color - | color - |
![tert-Butyl 4-[3-chloro-4-(methoxycarbonyl)phenyl]-1-piperazinecarboxylate AldrichCPR](/deepweb/assets/sigmaaldrich/product/structures/133/919/45475e69-def5-4dc1-8ff5-87553d47da1c/640/45475e69-def5-4dc1-8ff5-87553d47da1c.png)
![tert-Butyl 4-[2-chloro-4-(methoxycarbonyl)phenyl]-1-piperazinecarboxylate AldrichCPR](/deepweb/assets/sigmaaldrich/product/structures/884/171/353dcdc4-8068-49b1-bce9-2aa6eb463679/640/353dcdc4-8068-49b1-bce9-2aa6eb463679.png)
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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