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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Check Cart for Availability | € 119,00 € 101,15 |
25 mg | Check Cart for Availability | € 465,00 |
About This Item
Empirical Formula (Hill Notation):
C8H14CuN6S2
CAS Number:
Molecular Weight:
321.91
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
€ 101,15
List Price€ 119,00Save 15%Web-Only Promotion
Check Cart for Availability
Product Name
Cu-ATSM, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
color
, brown to dark red-brown
solubility
DMSO: 0.5 mg/mL, clear (warmed)
storage temp.
2-8°C
Biochem/physiol Actions
Cu-ATSM is an orally bioavailable, blood-brain barrier permeable complex that specifically inhibits the action of peroxynitrite on Cu,Zn superoxide dismutase (SOD1) and subsequent nitration of cellular proteins. CuII(ATSM) significantly delayed onset of disease (paralysis and prolonged lifespan) in amyotrophic lateral sclerosis (ALS) mice model. Also, Cu-ATSM was reported to lower lipid peroxidation in a model of ischemicreperfusion injury. Cu-ATSM subsequently was shown to inhibit ferroptosis with a potency similar to Liproxstatin-1.
Cu-ATSM is an orally bioavailable, blood-brain barrier permeable complex that specifically inhibits the action of peroxynitrite on Cu,Zn superoxide dismutase (SOD1).
1 of 1
This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC) | description >98% (HPLC) | description affinity isolated antibody, buffered aqueous solution |
| form powder | form powder | form powder | form buffered aqueous solution |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay >98% (HPLC) | assay - |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. −20°C |
| solubility DMSO: 0.5 mg/mL, clear (warmed) | solubility DMSO: 2 mg/mL, clear (Warmed) | solubility DMSO: 10 mg/mL, clear | solubility - |
| color , brown to dark red-brown | color , Faint brown to dark red | color white to light brown | color - |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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