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SAB4301218

Sigma-Aldrich

Anti-HSPG2 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

HSPG, PLC, SJA, SJS, SJS1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

469 kDa

species reactivity

mouse, human

concentration

3.2 mg/mL

technique(s)

immunohistochemistry: 1:50- 1:200
western blot: 1:200-1:1000 (Cell Lysate)

isotype

IgG

accession no.

NP_001278789.1

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... HSPG2(3339)

Specificity

The antibody detects endogenous levels of total HSPG2 protein.

Immunogen

Synthetic peptide corresponding to residues near the C terminal of human heparan sulfate proteoglycan 2

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Rossano Lattanzio et al.
BMC cancer, 19(1), 747-747 (2019-08-01)
Phospholipase Cγ1 (PLCγ1) is highly expressed in human tumours. Our previous studies reported that both stable and inducible PLCγ1 down-regulation can inhibit formation of breast-cancer-derived experimental lung metastasis. Further, high expression of PLCγ1 and its constitutively activated forms (i.e., PLCγ1-pY1253
Joseph G L Hunter et al.
PeerJ, 7, e6600-e6600 (2019-04-05)
Necrotic enteritis (NE) is caused by type A strains of the bacterium Clostridium perfringens. Total global economic losses to the poultry industry due to NE is estimated to be over two billion dollars annually. Traditionally, NE has been effectively controlled
Shujun Peng et al.
Molecular therapy. Nucleic acids, 16, 481-493 (2019-05-06)
Myogenesis is a complex and precisely orchestrated process that is highly regulated by several non-coding RNAs and signal pathways. Circular RNAs (circRNAs) represent a novel subclass of endogenous non-coding RNAs that have been identified in multiple species and tissues and
Eriong Lee-Vergés et al.
International journal of cancer, 144(11), 2762-2773 (2018-11-24)
The Bruton's tyrosine kinase (BTK) inhibitor ibrutinib has been shown to be highly effective in patients with chronic lymphocytic leukemia (CLL) and is approved for CLL treatment. Unfortunately, resistance and intolerance to ibrutinib has been observed in several studies, opening
Luo Li et al.
Journal of cellular physiology (2019-01-27)
Most prostate cancers (Pcas) develop into castration-resistant prostate cancer (CRPC) after receiving androgen deprivation therapy (ADT). The expression levels of PLCε and wnt3a are increased in Pca and regulate androgen receptor (AR) activity. However, the biological function and mechanisms of

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