Synthetic peptide directed towards the middle region of human TMEM144
Biochem/physiol Actions
TMEM144 belongs to the TMEM144 family. It is a multi-pass membrane protein.
Sequence
Synthetic peptide located within the following region: LSTVHHRIVGCSLAVISGVLYGSTFVPIIYIKDHSKRNDSIYAGASQYDL
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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Humans and mice with loss of function mutations in GPR54 (KISS1R) or kisspeptin do not progress through puberty, caused by a failure to release GnRH. The transcriptional networks regulated by these proteins in the hypothalamus have yet to be explored
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