Synthetic peptide directed towards the N terminal region of human ATP11B
Biochem/physiol Actions
P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-91 BI861412.1 1-91 92-104 AF156548.1 1-13 105-809 BC042180.1 105-809 810-1001 AF156548.1 719-910 1002-1244 BX489704.1 417-659 1245-1346 BF372979.1 79-180 1347-1791 BU431705.1 43-487 1792-4720 AB023173.1 22-2950 4721-6422 AL133061.1 2205-3906 6423-7314 AB023173.1 4651-5542 7315-7368 AL133061.1 4799-4852
Sequence
Synthetic peptide located within the following region: DIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETA
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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