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S2196

Anti-Sodium Channel NaV1.9 antibody produced in rabbit

affinity isolated antibody, lyophilized powder

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Synonym(s):

Anti-NAN, Anti-SNS2

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50 μL
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200 μL
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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
5

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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

rat

technique(s)

western blot: 1:200 using rat DRG lysates

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SCN11A(11280)
mouse ... Scn11a(24046)
rat ... Scn11a(29701)

General description

Sodium Channel NaV1.9 is a threshold channel, that is expressed in dorsal root ganglion neurons , peripheral nociceptive neurons and visceral afferents. It is also called as SNS and NaN. It is encoded by SCN11A (sodium voltage-gated channel subunit 11) and is located on human chromosome 3p22.

Immunogen

peptide CNGDLSSLDVAKVKVHND corresponding to residues 1748-1765 of rat Nav1.9. This sequence has 15/18 residues identical in mouse and 14/18 residues identical in human.

Biochem/physiol Actions

Sodium Channel NaV1.9 participates in pain at the time of inflammation. Downregulation of Nav1.9 is observed in Hirschsprung′s disease.

Physical form

Lyophilized from phosphate buffered saline, pH 7.4, with 1% bovine serum albumin, and 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item
S1946S0438S6936
description

affinity isolated antibody, lyophilized powder

description

affinity isolated antibody, lyophilized powder

description

affinity isolated antibody, lyophilized powder

description

affinity isolated antibody, lyophilized powder

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

Gene Information

human ... SCN11A(11280)
mouse ... Scn11a(24046)
rat ... Scn11a(29701)

Gene Information

human ... SCN5A(6331)

Gene Information

human ... SCN8A(6334)
mouse ... Scn8a(20273)
rat ... Scn8a(29710)

Gene Information

rat ... Scn1a(81574)

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder


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Storage Class

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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