Skip to Content
Merck
All Photos(1)

Key Documents

P7794

Sigma-Aldrich

Penicillin G potassium salt

Penicillin G potassium salt

powder, suitable for cell culture, BioReagent

Synonym(s):

Benzylpenicillin potassium salt

Sign Into View Organizational & Contract Pricing

Select a Size

1000000 UNITS
€34.80
10000000 UNITS
€58.70
100000000 UNITS
€320.00

€34.80


Estimated to ship on27 March 2025


Request a Bulk Order

Select a Size

Change View
1000000 UNITS
€34.80
10000000 UNITS
€58.70
100000000 UNITS
€320.00

About This Item

Empirical Formula (Hill Notation):
C16H17KN2O4S
CAS Number:
Molecular Weight:
372.48
Beilstein:
3832841
EC Number:
MDL number:
UNSPSC Code:
12352207
eCl@ss:
34010400
PubChem Substance ID:
NACRES:
NA.76

€34.80


Estimated to ship on27 March 2025


Request a Bulk Order

Product Name

Penicillin G potassium salt, powder, BioReagent, suitable for cell culture

product line

BioReagent

Quality Level

form

powder

potency

1440-1680 units per mg

technique(s)

cell culture | mammalian: suitable

antibiotic activity spectrum

Gram-positive bacteria

Mode of action

cell wall synthesis | interferes

SMILES string

[K+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O

InChI

1S/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1

InChI key

IYNDLOXRXUOGIU-LQDWTQKMSA-M

Looking for similar products? Visit Product Comparison Guide

General description

Chemical structure: ß-lactam

Application

Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans.

Biochem/physiol Actions

Mode of Action: Penicillin G acts by inhibiting cell wall synthesis through binding to penicillin binding proteins (PBPs), inhibiting peptidoglycan chain cross-linking.

Antimicrobial spectrum: This product is active against gram-positive and gram-negative bacteria.

Caution

Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for more lengthy periods. Solutions are stable at 37°C for 3 days. The potassium salt is soluble in H2O at 100 mg/mL.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Lavinia Florina Călinoiu et al.
Biomolecules, 10(1) (2019-12-28)
The aim of the present paper was to identify the major polyphenolic compounds and investigate the antioxidant, antimutagenic, and antimicrobial activities of industrially-derived cereal byproducts-wheat bran (WB) and oat bran (OB)-before (fresh) and after thermal processing (TP) (10 min, 80
R Comunian et al.
Journal of dairy science, 93(12), 5644-5650 (2010-11-26)
Antibiotics are widely used for therapeutic and prophylactic purposes in dairy animals. The presence of residual antibiotics in milk could cause potentially serious problems in human health and have technological implication in the manufacturing of dairy products. The aim of
Yulei Zhao et al.
American journal of translational research, 13(6), 7077-7082 (2021-07-27)
To explore the CD200/CD200R expression level in the peripheral blood mononuclear cells (PBMC) of hematological malignancy patients and to analyze its mechanism of action. Thirty hematological malignancy patients who were hospitalized in our hospital from June 2019 to December 2019
Sammy Detry et al.
Biochemical pharmacology, 165, 240-248 (2019-03-20)
The four core members of the Interleukin-12 (IL-12) family of cytokines, IL-12, IL-23, IL-27 and IL-35 are heterodimers which share α- and β-cytokine subunits. All four cytokines are immune modulators and have been proposed to play divergent roles in inflammatory
Bianca-Eugenia Ștefănescu et al.
Plants (Basel, Switzerland), 9(9) (2020-09-17)
Blueberries have seen an ascending production line boosted by World Health Organization (WHO) approvals for their contributions to a healthy diet and the evidence that they act against different diseases. This increase resulted in significant amounts of discarded leaves, which

Questions

1–2 of 2 Questions  
  1. ¿A qué temperatura debe de almacenarse este producto en polvo y por cuánto tiempo es estable?

    1 answer
    1. This product may be stored in room temperature. Concerning expiration, this product is assigned a product retest date. Products that, while considered stable, may be subject to degradation over time are assigned a periodic retest date to confirm quality. The lot specific retest date is reported on the Certificate of Analysis. Please see the link below to review a sample or lot specific Certificate:
      https://www.sigmaaldrich.com/product/sigma/p7794#product-documentation

      Helpful?

  2. Is the reported potency for P7794 Penicillin G potassium salt based on the anhydrous/dried form, or is it based on an as-it-is basis? Also, what does the "S" signify in U/mgS for the reported potency results?

    1 answer
    1. The potency test is reported on an "as is" basis. The "S" in U/mgS stands for unit per milligram solid.

      Helpful?

Reviews

Active Filters

  1. 1 Ratings-Only Review

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service