M1695
MAZ51
≥98% (HPLC), solid
Synonym(s):
3-(4-Dimethylaminonaphthalen-1-ylmethylene)-1,3-dihydroindol-2-one
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About This Item
Assay
≥98% (HPLC)
form
solid
color
orange
solubility
DMSO: 11 mg/mL
storage temp.
2-8°C
SMILES string
CN(C)c1ccc(\C=C2/C(=O)Nc3ccccc23)c4ccccc14
Biochem/physiol Actions
Cell-permeable VEGFR-3 inhibitor. At low concentration ≥ 5 μM), it specifically blocks VEGF-C- and VEGF-D-induced phosphorylation of VEGFR-3, but not VEGFR-2, in PAE cells. It partially blocks VEGFR-2 phosphorylation only at higher concentrations (50 μM).
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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